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Online Movement Training With Video for People With Parkinson's Disease

Tests watching and imagining movements, delivered online, in people with Parkinson's disease.

Key facts

Who runs it
Istituto Clinico Humanitas
Where
Rozzano, ItalySee the site
Trial code
Registry title
Effects of Action Observation Training and Motor Imagery Delivered by Telerehabilitation in Patients with Parkinson's Disease
Status
Not yet recruiting
People taking part
60 people, planned
Started
1 Mar 2025
Planned end
Sept 2026
Type of study
Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Action Observation Training
  • Action Observation and Motor Imagery
  • Exercise
Record updated
7 February 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with Parkinson's disease who can do video-guided exercises at home by telerehabilitation. It tests two exercise methods against a control group.

Sex
Men and women can join.
Disease stage
Clinically definite Parkinson's disease (Movement Disorders Society criteria), Hoehn and Yahr scale below 4.
Earlier treatment
A stable medication regimen for at least 4 weeks.
Biomarker or test result
Montreal Cognitive Assessment (MoCA) score of 26 or higher.

Main reasons for not taking part

  • Systemic, psychiatric, or other neurological illnesses that affect movement or daily function
  • A history of substance abuse that affects thinking or following the trial
  • Visual disturbances
  • Head tremor

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • diagnosis of clinically definite PD according to the Movement Disorders Society criteria
  • Hoehn and Yahr scale <4
  • Montreal Cognitive Assessment, MoCA ≥ 26
  • a stable medication regimen for at least 4 weeks

Who cannot take part

  • Systemic, psychiatric, or other neurological illnesses influencing motor or functional performance
  • a history of substance abuse influencing cognition or compliance
  • visual disturbances
  • head tremor

Where in Italy

  • Istituto Clinico HumanitasRozzano, ItalyContact: Roberto GattiNo longer taking part

About the trial

What the trial wants to find out

The goal of this clinical trial is to investigate the efficacy on motor and postural tasks of Action Observation Training (AOT) and Action Observation combined with Motor Imagery (AOMI) delivered by telerehabilitation in patients with Parkinson Disease.

Read full original descriptionShow less

* The primary endpoint will be mobility measured with the Timed Up and Go (TUG) test (differences before and after telerehabilitation treatment period). * In addition, clinical and functional measures, instrumental analysis of gait and posture, and Magnetic Resonance Imaging (MRI) correlates will be assessed.

Participants will be asked to undergo 24 telerehabilitation sessions, cadenced 3 per week, over an 8-week period. In the two experimental groups (AOT and AOMI), each telerehabilitation session will encompass 4 motor tasks, each containing the observation of a video clip immediately followed by the patient's execution or imagination of the same exercises. Patients in the control group will be instructed to perform the same exercises after watching videos showing landscapes

The 3 groups in the trial

  • Action Observation Training Group (AOT)Treatment being tested

    Patients in this group will be exposed to four video presentations showing movements with different degrees of focal vs. postural components. The patients will imitate immediately after watching.

    Treatment: Action Observation Training

  • Action Observation and Motor Imagery Group (AOMI)Treatment being tested

    Patients in this group will be exposed to four video presentations showing movements with different degrees of focal vs. postural components. The patients will mentally rehearse what they saw in the videos immediately after watching.

    Treatment: Action Observation and Motor Imagery

  • Control groupExisting treatment, for comparison

    Patients in this group will be exposed to four video presentations showing landscape. Patients will perform the same exercise of AOT groupimmediately after watching.

    Treatment: Exercise

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Effects of Action Observation Training and Motor Imagery Delivered by Telerehabilitation on Mobility, Posture and Brain Plasticity in Patients with Parkinson's Disease
Plain-language title
Online Movement Training With Video for People With Parkinson's DiseaseGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
7 February 2025