Compares spacers for delivering an asthma inhaler in patients with asthma
Tests different spacer devices used with a salbutamol inhaler in people with asthma.
Plain-language title generated from the registry record
Registry title: Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
Key facts
- Where
- Banī Suwayf, EgyptSee the site
- Phase
- Phase 4
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 80 years old?
Source: NCT06816342, who can take part
Where in Egypt
- Beni-Suef University HospitalBanī Suwayf, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Beni-Suef University
- Trial code
- NCT06816342
- Record updated
- 10 February 2025
- Original description
* The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI. in young children and adult asthmatic patients The main questions it aims to answer are:Read full original descriptionShow less
Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
* The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI. in young children and adult asthmatic patients The main questions it aims to answer are:
1. Measuring total emitted dose emitted from pMDI alone and attached to spacers. 2. Determining the pharmacokinetic parameter of aerosol delivered by different spacers. 3. Determining the lung bioavailability of aerosol delivered by different spacers. 4. Determining the systemic bioavailability of aerosol delivered by different spacers. 5. Determining the lung function after aerosol delivered by different spacers. 6. Determining the safety Researchers will compare salbutamol amount delivered using pMDI alone and pMDI connected to differents spacers to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs.
Participants will asked to * inhale salbutamol through pMDI alone and pMDI connected to different spacers * perform lung function test using spirometer * urine samples will be taken from patients 30 minutes and 24 hours after dose inhalation. * use pulse oximeter to measure heart rate
Inclusion: Mild and moderate asthmatic patients aged from 6 - 80 year old.
Exclusion: recent abdominal surgery; ischemic heart disease; hepatic or renal impairment; hypersensitivity to salbutamol; Severe asthmatics or patients admitted to an intensive care unit; inability to perform properly the pulmonary function tests.