Studying Steroid Hormones and Environmental Chemicals in Endometriosis
Compares blood, urine and vaginal samples in women with endometriosis.
Plain-language title generated from the registry record
Registry title: Pilot Study to Characterize the Endometriosis Steroidome and Its Link to Endocrine Disruptors and Vaginal Dysbiosis
Key facts
- Where
- Nantes, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT06820450, who can take part
Where in France
- CHU de NantesNantes, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nantes University Hospital
- Trial code
- NCT06820450
- Record updated
- 24 June 2026
- Original description
Endometriosis is a systemic, steroid-dependent, inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, affecting approximately 10 % of women of childbearing age. The etiology and pathophysiology of endometriosis is not completely understood to support effective treatment and prevention strategies. Despite the steroid dependency, little is known concerning the underlying metabolism of estrogen and other tightly related steroids. Moreover, shortening the long diagnostic delays is a major priority in endometriosis research.Read full original descriptionShow less
STERONLINE: Steroidome and Exposome of Endometriosis Single-center Case-control Study
Endometriosis is a systemic, steroid-dependent, inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, affecting approximately 10 % of women of childbearing age. The etiology and pathophysiology of endometriosis is not completely understood to support effective treatment and prevention strategies. Despite the steroid dependency, little is known concerning the underlying metabolism of estrogen and other tightly related steroids. Moreover, shortening the long diagnostic delays is a major priority in endometriosis research.
Inclusion: Women aged 18 to 45; Free, informed and written consent from the patient to participate in the study; Good understanding of the French language; Patient affiliated to or benefiting from a social security or similar scheme; Specific inclusion criteria for each group:; Group 1. Controls; Women with no laparoscopically confirmed signs suggestive of deep endometriosis; No clinico-biological criteria in favour of a diagnosis of endometriotic disease, nor any radiological signs (ultrasound or MRI) suggestive of endometriosis; Group 2. Cases of deep endometriosis; Newly diagnosed women (less than 12 months); Severe, deep endometriotic pathology with surgical indication (clinical examination, imaging tests, pre-operative findings).
Exclusion: Presence of other hormone-dependent pathologies (e.g. breast cancer, PCOS); Acute infection; Intercurrent diagnosis of pregnancy.