Tests olanzapine dosing schedules in people with schizophrenia
Compares different olanzapine dose-increase schedules in adults with schizophrenia.
Plain-language title generated from the registry record
Registry title: A Clinical Trial to Evaluate the Safety and Efficacy of Olanzapine Titration Schedule in Patients With Schizophrenia
Key facts
- Where
- Daegu and Guri-si, South KoreaSee the 2 sites
- Phase
- Phase 2
Where in South Korea
- Kyungbook National university hospitalDaegu, South KoreaTaking people
- Hanyang University Guri HospitalGuri-si, South KoreaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Boryung Pharmaceutical Co., Ltd
- Trial code
- NCT06821945
- Record updated
- 15 September 2025
- Original description
The objective of this clinical trial is to evaluate the safety and efficacy of olanzapine titration schedule in patients with schizophreniaRead full original descriptionShow less
A Multi-Center, Randomized, Double-Blind, Parallel-Design, Exploratory Clinical Trial to Evaluate the Safety and Efficacy of Olanzapine Titration Schedule in Patients With Schizophrenia
The objective of this clinical trial is to evaluate the safety and efficacy of olanzapine titration schedule in patients with schizophrenia
Inclusion: Of patients with schizophrenia in accordance with DSM(Diagnostic and Statistical Manual of Mental Disorders)-5 diagnostic criteria, who are judged that administration of low dose is more appropriate than initial recommended dose or standard titration dose of olanzapine to consider medical conditions by investigator; Patients with the duration of schizophrenia for more than 1 year at screening visit(Visit 1).
Exclusion: Patients diagnosed schizophrenia spectrum and other psychotic disorder(e.g. schizoaffective disorder, etc.), bipolar disorder, depressive disorder, etc., in accordance with DSM(Diagnostic and Statistical Manual of Mental Disorders)-5 diagnostic criteria at screening visit(Visit 1); Patients with a history of hospitalization for worsening schizophrenia within 12 weeks at screening visit(Visit 1).