An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects
Key facts
- Where
- Zabrze, PolandSee the site
Where in Poland
- Silesian Center for Heart DiseasesZabrze, PolandContact: Raymond N. Haddad, MD, MHSc, PhDcTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Fondation Hôpital Saint-Joseph
- Trial code
- NCT06823635
- Record updated
- 8 September 2026
- Original description
The international multicenter registry aims to gather real-world data on patient outcomes and assess the procedural success and performance of various device occluders used in the transcatheter treatment of pediatric and adult patients with perimembranous ventricular septal defects (PmVSD).Read full original descriptionShow less
The international multicenter registry aims to gather real-world data on patient outcomes and assess the procedural success and performance of various device occluders used in the transcatheter treatment of pediatric and adult patients with perimembranous ventricular septal defects (PmVSD).
Inclusion: Patients with perimembranous ventricular septal defects (PmVSD) diagnosed by 2D transthoracic echocardiography according to established classification systems, who provided informed consent and underwent transcatheter closure using any commercially available occluder devices (whether specifically designed for this indication or used off-label), with follow-up according to local hospital protocols; Defect size between 3 mm and <20 mm on the left ventricular side, as measured by 2D echocardiography; Age ≥1 month and body weight ≥5 kg; Left-to-right ventricular shunt.
Exclusion: Failure to attend any follow-up visit post-discharge; Patients or legal guardians refusing the use of personal data for research purposes.