Tests a heart procedure to prevent irregular heartbeat after heart surgery
Tests a radiofrequency heart procedure to prevent atrial fibrillation after heart surgery.
Plain-language title generated from the registry record
Registry title: Prophylactic Radiofrequency Left Atrial Posterior Wall Isolation to Prevent Atrial Fibrillation After Cardiac Surgery
Key facts
- Where
- Moscow, RussiaSee the site
Where in Russia
- Department of Cardiac Surgery, Yudin HospitalMoscow, RussiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vasily I. Kaleda
- Trial code
- NCT06823778
- Record updated
- 21 February 2025
- Original description
The goal of this clinical trial is to learn if an epicardial radiofrequency left atrial posterior wall isolation (box lesion ablation) prevents atrial fibrillation after cardiac surgery. The main question it aims to answer is:Read full original descriptionShow less
Prophylactic Radiofrequency Left Atrial Posterior Wall Isolation (box Lesion Ablation) to Prevent Atrial Fibrillation After Cardiac Surgery (PROBOX): a Randomized Controlled Trial
The goal of this clinical trial is to learn if an epicardial radiofrequency left atrial posterior wall isolation (box lesion ablation) prevents atrial fibrillation after cardiac surgery. The main question it aims to answer is:
- Does box lesion ablation lower the number of patients experiencing de-novo atrial fibrillation requiring any treatment after cardiac surgery? Researchers will compare box lesion ablation to no ablation to see if ablation prevents postoperative atrial fibrillation.
Participants will undergo ablation or no ablation at the time of other cardiac surgery.
Data will be collected while in hospital. Additional information will be collected on 30th day after surgery by telephone call or during a visit.
Inclusion: All patients undergoing cardiac surgery by a single surgeon (V.K.); Informed consent.
Exclusion: Off-pump surgery; Emergent/salvage surgery; History of atrial fibrillation/flutter; Minimally invasive approach; Severe pericardial adhesions.