Tracks eye blood vessels, vision and eye structure over time in glaucoma
Observes changes in the eyes of people with glaucoma or high eye pressure over time.
Plain-language title generated from the registry record
Registry title: Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients
Key facts
- Where
- Genoa, Milan, Novara, Rome, and Sassari, ItalySee the 5 sites
Where in Italy
- Clinica Oculistica, DiNOGMI, Università di GenovaGenoa, ItalyNo longer taking part
- Ospedale San Paolo - ASST Santi Paolo e CarloMilan, ItalyNo longer taking part
- Ospedale Maggiore della CaritàNovara, ItalyNo longer taking part
- IRCCS-Fondazione GB BiettiRome, ItalyNo longer taking part
- Azienda Ospedaliera Universitaria di Sassari, Dipartimento di Medicina, Chirurgia e Farmacologia Università di SassariSassari, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mario Stirpe
- Trial code
- NCT06827535
- Record updated
- 18 February 2025
- Original description
This is an observational study involving patients with glaucoma, those with ocular hypertension and healthy subjects.Read full original descriptionShow less
Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients
This is an observational study involving patients with glaucoma, those with ocular hypertension and healthy subjects.
The aim of the study is the long term evaluation of functional, vascular and morphological changes in glaucoma and ocular hypertensive patients, compared to healthy subjects, to analyze the temporal relationship of these changes.
Inclusion: Diagnosis of primary glaucoma (open or closed angle) or secondary glaucoma (pseudoexfoliative or pigmentary) defined by the presence of a glaucomatous defect of the optic nerve and/or a perimetric glaucomatous defect as defined by the European guidelines; Diagnosis of ocular hypertension (defined by the presence of intraocular pressure values≥22 mmHg, optic nerve and visual field examination within normal limits); No Optic nerve disease and IOP<21mmHg for healthy subjects; Age>18 years; Able to read and sing the informed consent form.
Exclusion: Previous eye surgery, except glaucoma surgery or removal of cataracts performed more than 6 months prior to enrollment; BCVA <5/10; Other pathologies that can cause alterations of the optic nerve or visual field defects; Presence of maculopathies; Inability to perform visual field tests; Opacity of the dioptric media such that it is not possible to perform reliable OCT and OCTA of acceptable quality.