Frontlight ResearchEarly access
Taking people in United StatesNo phase
Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy
Key facts
- Who runs it
- Loma Linda University
- Where
- Loma Linda and Los Angeles, United StatesSee the 2 sites
- Trial code
- Status
- Recruiting
- People taking part
- 80 people, planned
- Starts
- Dec 2026
- Expected to end
- Sept 2029
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Radical inguinal orchiectomy
- Radical external oblique fascia sparing orchiectomy
- Record updated
- 10 November 2026
Who can take part
- Age
- 18 years and older
- Sex
- Men only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Participants undergoing radical orchiectomy for suspected testicular malignancy
- Testicular malignancy can be germ cell tumor or non germ cell tumors, including paratesticular tumors as long as a radical orchiectomy is planned
- Participants over 18 years of age who can provide informed consent
- Participants not currently using opiates for another reason
- Regional and metastatic patients are allowed, as long as participant does not require opiates for pain related to metastatic disease
- No contraindication for participant to receive standardized medication pathway in the peri-operative period
Who cannot take part
- History of illicit substance abuse (including prior opioid abuse) except for marijuana
- Participants who underwent chemotherapy or radiotherapy prior to orchiectomy
- Clinical T4 disease
- Opioid use within 1 month of study enrollment
- Participants with large testis masses requiring skin incision larger than 8 cm in size
- Participants with large testis masses requiring orchiectomy through an incision other than the standard transverse inguinal incision (i.e. hockey stick incision, vertical incision)
Where in United States
- Loma Linda UniversityLoma Linda, United StatesContact: Muhannad Alsyouf, MDTaking people
- University of Southern CaliforniaLos Angeles, United StatesContact: Siamak Daneshmand, MDTaking people
About the trial
What the trial wants to find out
The purpose of this study is to evaluate the difference in patient-reported postoperative outcomes between two standard-of-care surgical techniques for radical orchiectomy (inguinal orchiectomy versus external oblique fascia sparing orchiectomy) for treatment of patients with suspected testicular malignancy. The main questions it aims to answer are:
Read full original descriptionShow less
1. Does sparing the external oblique fascia during orchiectomy reduce pain after surgery? 2. Is there a difference in narcotic consumption after surgery? 3. Is there a difference in neuropathic pain after surgery? 4. Is there a difference in complications after surgery?
The 2 groups in the trial
- Radical inguinal orchiectomyExisting treatment, for comparison
- Radical external oblique fascia sparing orchiectomyExisting treatment, for comparison
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Patient Reported Experiences With Sparing ExteRnal Oblique Fascia Vs Standard Inguinal OrchiEctomy
- Record updated
- 10 November 2026