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Testing a Tailored Bypass Length for Weight Loss Surgery

Tests a surgery length adjusted to each patient's small bowel in adults with obesity.

Plain-language title generated from the registry record
Registry title: Tailored One Anastomosis Gastric Bypass

Key facts

Where
Tel Aviv, IsraelSee the site

Where in Israel

  • Tel-Aviv Sourasky Medical CenterTel Aviv, IsraelTaking people

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Trial details

Who runs it
Tel-Aviv Sourasky Medical Center
Trial code
NCT06829381
Record updated
24 July 2025
Original description
One Anastomosis Gastric Bypass (OAGB) is the most common metabolic and bariatric surgery (MBS) in Israel, recognized for its effectiveness in achieving sustainable weight loss and mitigating obesity-related diseases. The metabolic outcomes of OAGB are significantly influenced by the length of the biliopancreatic limb (BPL). The objective of this study is to determine whether tailoring the BPL length to the total small bowel length (TSBL) results in more effective weight loss compared to patients undergoing OAGB with a fixed BPL of 180 cm. Efficacy and safety of this approach will also be evaluated, ensuring it does not lead to long-term morbidity or negatively impact patients' quality of life.Read full original descriptionShow less

Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial

One Anastomosis Gastric Bypass (OAGB) is the most common metabolic and bariatric surgery (MBS) in Israel, recognized for its effectiveness in achieving sustainable weight loss and mitigating obesity-related diseases. The metabolic outcomes of OAGB are significantly influenced by the length of the biliopancreatic limb (BPL). The objective of this study is to determine whether tailoring the BPL length to the total small bowel length (TSBL) results in more effective weight loss compared to patients undergoing OAGB with a fixed BPL of 180 cm. Efficacy and safety of this approach will also be evaluated, ensuring it does not lead to long-term morbidity or negatively impact patients' quality of life.

Inclusion: Adults (≥18 years) undergoing OAGB.

Exclusion: Patients <18 years, pregnant women, or those lacking decision-making capacity Prior bariatric surgery Short bowel (<450 cm).

ClinicalTrials.gov NCT06829381