Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Key facts
- Where
- A Coruña, Badalona, Burgos, Córdoba, Manises, Marbella, Murcia, Pamplona, Sabadell, Santa Cruz de Tenerife, Seville, and Valladolid, SpainSee the 12 sites
Where in Spain
- Complejo Hospitalario Universitario A Coruña /ID# 272040A Coruña, SpainTaking people
- Institut Català d'Oncologia (ICO) - Badalona /ID# 272043Badalona, SpainTaking people
- Hospital Universitario De Burgos /ID# 272066Burgos, SpainTaking people
- Hospital Universitario Reina Sofia /ID# 272051Córdoba, SpainTaking people
- Hospital de Manises /ID# 272046Manises, SpainTaking people
- Hospital Costa del Sol /ID# 272431Marbella, SpainTaking people
- Hospital General Universitario Morales Meseguer /ID# 272466Murcia, SpainTaking people
- Hospital Universitario de Navarra /ID# 272041Pamplona, SpainTaking people
- Hospital Universitari Parc Tauli /ID# 272044Sabadell, SpainTaking people
- Hospital Universitario Nuestra Señora de Candelaria /ID# 272413Santa Cruz de Tenerife, SpainTaking people
- Hospital Universitario de Valme /ID# 272050Seville, SpainTaking people
- Hospital Clinico Universitario de Valladolid /ID# 272042Valladolid, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- AbbVie
- Trial code
- NCT06830759
- Record updated
- 17 February 2026
- Original description
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections) and the most common type of non-Hodgkin lymphoma. Follicular Lymphoma (FL) is a slow-growing type of non-Hodgkin lymphoma. The purpose of this study is to assess the real-world effectiveness of subcutaneous epcoritamab in adult participants with advanced DLBCL and FL.Read full original descriptionShow less
EpcoReal: A Multi-country, Prospective Observational Study of Epcoritamab in NHL Comprising Two Patient Cohorts (3L+ (D)LBCL and 3L+ FL)
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections) and the most common type of non-Hodgkin lymphoma. Follicular Lymphoma (FL) is a slow-growing type of non-Hodgkin lymphoma. The purpose of this study is to assess the real-world effectiveness of subcutaneous epcoritamab in adult participants with advanced DLBCL and FL.
Epcoritamab is an investigational drug being developed for treating participants with DLBCL and FL. Approximately 700 participants will be enrolled in approximately 80 sites across 12-20 countries globally.
Participants will receive epcoritamab as prescribed by their physician in accordance with local country label. Participants will be followed for up to 3 years.
There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
Inclusion: Participants who are scheduled to be treated with epcoritamab for Treatment after two or more prior lines of therapy 3L+ diffuse large B-cell lymphoma ((D)LBCL) or 3L+ Follicular lymphoma (FL); Treatment with epcoritamab should be administered in accordance with the approved local label in the participating country; The decision to treat the participant should have been made by the clinician prior to, and independently of any decision to approach the participant to participate in this study.
Exclusion: Participation in a concurrent interventional clinical trial (not including non-interventional/ observational study, PMOS, or registry participation) from enrollment and throughout the study; Any condition included in the contraindications section of the approved local epcoritamab label in the participating country.