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Tests a phone app based on cognitive behavioral therapy for depression

Tests a phone app of talk-therapy exercises in people aged 14 to 60 with depression.

Plain-language title generated from the registry record
Registry title: Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study

Key facts

Where
Beijing, ChinaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 14 and 60 years old?

Source: NCT06831435, who can take part

Where in China

  • Peking University Sixth HostipalBeijing, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Peking University
Trial code
NCT06831435
Record updated
15 December 2025
Original description
The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression. The digital cognitive behavioral therapy in this study is conducted based on a self-developed mobile applet. The therapy is developed by psychotherapists, which is conducted for a total of 8 weeks, with weekly sessions including AI-guided course work and homework. This study aims to evaluate the therapeutic effects of CBT-based digital products for depression in patients through a real-world study, and to explore its genetic and neuroimaging mechanisms.Read full original descriptionShow less

Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study

The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression. The digital cognitive behavioral therapy in this study is conducted based on a self-developed mobile applet. The therapy is developed by psychotherapists, which is conducted for a total of 8 weeks, with weekly sessions including AI-guided course work and homework. This study aims to evaluate the therapeutic effects of CBT-based digital products for depression in patients through a real-world study, and to explore its genetic and neuroimaging mechanisms.

Inclusion: Aged 14-60 years (including 14 and 60), no gender restriction; HAMD >= 14; Written informed consent obtained from the patient; written informed consent obtained from the guardian for minors.

Exclusion: Persons with severe suicidal tendencies (item 10 of the MADRS scale ≥ 5).

ClinicalTrials.gov NCT06831435