Checks for cancer spread in the belly using keyhole surgery in cervical cancer
Looks at keyhole surgery to detect belly spread in adults with advanced cervical cancer.
Plain-language title generated from the registry record
Registry title: Detection of Peritoneal Metastases by Diagnostic LAparoscopy in Patients With Locally Advanced Cervical Carcinoma
Key facts
- Where
- Rome, ItalySee the site
Where in Italy
- Policlinico Agostino Gemelli IRCCSRome, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Trial code
- NCT06832397
- Record updated
- 18 February 2025
- Original description
The study hypothesizes that specific subgroups of LACC patients, (AJCC stage T3/T4, grade 3 tumors, and para-aortic lymph node involvement), have a higher prevalence of peritoneal metastasis. This peritoneal spread may serve as a prognostic factor, and diagnostic laparoscopy could improve staging accuracy, thereby guiding personalized treatment strategies and improving oncological outcomes.Read full original descriptionShow less
Prospective Observational Study On the Detection of Peritoneal Metastases by Diagnostic LAparoscopy in Specific Subgroups of Patients With Locally Advanced Cervical canceR
The study hypothesizes that specific subgroups of LACC patients, (AJCC stage T3/T4, grade 3 tumors, and para-aortic lymph node involvement), have a higher prevalence of peritoneal metastasis. This peritoneal spread may serve as a prognostic factor, and diagnostic laparoscopy could improve staging accuracy, thereby guiding personalized treatment strategies and improving oncological outcomes.
Inclusion: Cervical cancer AJCC stage T3/T4 and/or; Cervical cancer FIGO stage IB3 and IIA2-IVA grade 3 and/or; Cervical cancer FIGO stage IIIC2 (para-aortic lymph node metastasis). Lymph node will be considered pathologic when the short axis diameter is > 10 mm at MRI scan and/or SUV max >2.5 at PET/CT-scan; All cervical histology sub-types will be included; Stage assessment according to local Multidisciplinary Board; Age >18 years; Signature informed consent or substitute declaration on the consent form where applicable.
Exclusion: Patients with previous diagnosis of other cancers; Recurrent cervical cancer; Performance status ECOG >2; Pregnant women; Contraindications to diagnostic laparoscopy.