Comparing acupuncture and brain stimulation for migraine headache
Compares acupuncture and brain stimulation with tDCS in adults with migraine.
Plain-language title generated from the registry record
Registry title: Comparison of Neuromodulatory Treatment of Migraine Headache with Acupuncture and Transcranial Direct Current Stimulation
Key facts
- Where
- Ljubljana, SloveniaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with migraine who have never had acupuncture. It compares acupuncture and transcranial direct current stimulation (tDCS).
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Migraine with 4 migraine days per month.
- Earlier treatment
- No acupuncture in the past.
Main reasons for not taking part
- Severe psychiatric disorders
- Pacemaker
- Brain surgery with open skull in the past
- Brain stimulators
- Metal implants
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06834022, who can take part
Where in Slovenia
- Hospital dr. Petra DržajaLjubljana, SloveniaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Medical Centre Ljubljana
- Trial code
- NCT06834022
- Record updated
- 19 February 2025
- Original description
The goal of this clinical trial is to compare effects of the treatment with acupuncture and transcranial direct current stimulation (tDCS) in patients with migraine headache. The main questions it aims to answer are:Read full original descriptionShow less
Comparison of Neuromodulatory Treatment of Migraine Headache with Acupuncture and Transcranial Direct Current Stimulation
The goal of this clinical trial is to compare effects of the treatment with acupuncture and transcranial direct current stimulation (tDCS) in patients with migraine headache. The main questions it aims to answer are:
* is tDCS more effective than acupuncture/placebo? * is there any difference in venous blood inflammatory parameters (CGRP (calcitonin gene related peptide), IL (interleukine) -6, IL-8. IL-10, SAA (serum amyloid A) and ESR (erythrocyte sedimentation rate) before/after treatment? * could these inflammatory parameters function as biomarkers of disease and/or indicators of treatment's efficacy?
Participants will regularly fill out questionnaires (migraine diary) and their venous blood before/after treatment will be taken for analysis.
Researchers will compare the effects of sham and verus treatment of both methods before and after treatment.
Inclusion: 4 migraine days per month; no acupuncture in the past; understanding of study design and ability to give informed consent.
Exclusion: status post brain surgery with open skull; metal implants; biologic drugs; severe psychiatric disorders; pacemaker; brain stimulators; pregnancy.