Rhythmic Sound Cues to Study Walking in Stroke and Parkinson Patients
Compares rhythmic sound stimulation with no stimulation in adults with stroke or Parkinson disease.
Plain-language title generated from the registry record
Registry title: Clinical Study of Rhythmic Auditory Stimulation for Gait Disorders
Key facts
- Where
- Beijing, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 80 years old?
Source: NCT06837038, who can take part
Where in China
- Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- YiCheng Zhu
- Trial code
- NCT06837038
- Record updated
- 20 February 2025
- Original description
The aim of this clinical trial was to determine whether rhythmic auditory stimulation is effective in treating gait disorders in patients with post-stroke hemiplegia, primary Parkinson's disease, and various parkinsonism syndromes. The main questions it aims to answer are:Read full original descriptionShow less
Clinical Study of Rhythmic Auditory Stimulation for Gait Disorders
The aim of this clinical trial was to determine whether rhythmic auditory stimulation is effective in treating gait disorders in patients with post-stroke hemiplegia, primary Parkinson's disease, and various parkinsonism syndromes. The main questions it aims to answer are:
Does rhythmic auditory stimulation increase walking speed in patients with gait disorders? To determine whether rhythmic auditory stimulation is effective in treating gait disorders, researchers will compare a gait rhythmometer with an active control that does not receive rhythmic stimulation.
Participants will:
Gait training was conducted once a day for 15 minutes for 7 consecutive days Resting-state functional magnetic resonance imaging (fmri) was performed before and after treatment Feedback on subjective improvement at the end of the 7-day treatment
Inclusion: Age 50-80 years old; One or more strokes (cerebral infarction or cerebral hemorrhage), with the most recent stroke occurring at least 6 months earlier; Walking independently without a cane or walking aid with obvious gait asymmetry; 0.4m/s< baseline velocity <0.8m/s; Sufficient hearing, vision and comprehension to complete motor function tests; Patients were willing and able to participate in all study procedures and signed informed consent; No other rehabilitation treatment was received at present; Age 50-80 years old; PD met the diagnostic criteria of Chinese Diagnostic Criteria for Parkinson's Disease (2016 edition); Obvious panic gait, freezing gait or slow gait, but can walk independently without the use of a cane or walking aid; Hoehn-Yahr (H-Y) stage 2-4; 0.4m/s< baseline velocity <0.8m/s; Sufficient hearing, vision and comprehension to complete motor function tests; Patients were willing and able to participate in all study procedures and signed informed consent; No other rehabilitation treatment was received at present; Age 50-80 years old; All parkinsonism syndrome except primary Parkinson's disease, including but not limited to drug-induced parkinsonism, multiple system atrophy, cerebral small vessel disease-related parkinsonism, etc; obvious panic gait, freezing gait or slow gait, but can walk independently without the use of a cane or walking aid; 0.4m/s< baseline velocity <0.8m/s; Sufficient hearing, vision and comprehension to complete motor function tests; Be willing and able to participate in all study procedures and sign informed consent; No other rehabilitation treatment was received at present.
Exclusion: Uncontrolled hypertension; Myocardial infarction within the past 3 months; With bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc; Except for stroke, there was no parkinsonism, myasthenia gravis, poliomyelitis and other nervous system diseases affecting the walking function of patients; For primary Parkinson's disease (PD); Uncontrolled hypertension; Myocardial infarction within the past 3 months; With bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc; There was no stroke, myasthenia gravis, poliomyelitis and other neurological diseases affecting the walking function except for primary Parkinson's disease; For Parkinsonism syndrome:; Uncontrolled hypertension; Myocardial infarction within the past 3 months; With bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc; There was no stroke, myasthenia gravis, poliomyelitis and other neurological diseases that affected the walking function except for parkinsonism; Unable to cooperate with the motor function test; Unable to cooperate with the motor function test; Unable to cooperate with the motor function test.
For post-stroke hemiplegia.