AI-guided procedure for liver blood pressure problem in cirrhosis
Tests whether AI guidance helps place a shunt in adults with cirrhosis.
Plain-language title generated from the registry record
Registry title: AI-guided TIPS Procedure
Key facts
- Where
- Wuhan, ChinaSee the 3 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with liver cirrhosis and portal hypertension who need a TIPS procedure (a shunt placed inside the liver). It compares AI-guided TIPS with conventional blind-puncture TIPS.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- Portal hypertension related to cirrhosis, with a clinical need for a TIPS procedure.
Main reasons for not taking part
- Allergy or serious reaction to iodine contrast media or related drugs
- Pregnant or breastfeeding
- Unwilling or unable to sign informed consent
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06837974, who can take part
Where in China
- Wuhan Union HospitalWuhan, ChinaContact: Chuansheng ZhengNo longer taking part
- Wuhan Union Jinyinhu HospitalWuhan, ChinaContact: Huangxuan Zhao, PhDNo longer taking part
- Wuhan Union West HospitalWuhan, ChinaContact: Lei ChenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Trial code
- NCT06837974
- Record updated
- 20 February 2025
- Original description
The goal of this clinical trial is to learn if transjugular intrahepatic portosystemic shunt (TIPS)-guided AI model can guide TIPS procedure in adults better than conventional TIPS procedure (artificially blinded TIPS). TIPS surgical outcomes and intraoperative and postoperative complications will also be observed. The main questions it aims to answer are:Read full original descriptionShow less
Construction and Application of an AI Model for Guided TIPS Surgical Puncture: a Prospective Multicenter Randomized Controlled Trial
The goal of this clinical trial is to learn if transjugular intrahepatic portosystemic shunt (TIPS)-guided AI model can guide TIPS procedure in adults better than conventional TIPS procedure (artificially blinded TIPS). TIPS surgical outcomes and intraoperative and postoperative complications will also be observed. The main questions it aims to answer are:
* Does the AI model lower the number of punctures, radiation dose, and complications of participants undergo TIPS? * Does the AI model improve the efficacy of TIPS for participants?
Participants will:
* Take the TIPS by the guidance of the AI model or conventional manually blinded penetration (placebo) * The number of punctures, the success rate of the procedure, the radiation dose, intraoperative complications and postoperative complications within 3 months will be recorded * Intraoperative portal pressure gradient drop values, symptoms of ascites and rebleeding within 3 months after TIPS will be reported
Inclusion: Participants who require transjugular intrahepatic portosystemic shunt (TIPS) and meet the clinical indications for the procedure; Participants whose physical condition is suitable for TIPS.
Exclusion: Participants with a history of allergy or serious adverse reactions to iodine contrast media or other related drugs; Participants are pregnant or breastfeeding; Participants are unwilling or unable to sign informed consent.