Cannabidiol for bladder leakage after a recent spinal cord injury
Tests cannabidiol for urinary incontinence in people with a recent spinal cord injury.
Key facts
- Who runs it
- University of Wisconsin, Madison
- Where
- Madison, United StatesSee the site
- Trial code
- Registry title
- CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
- Status
- Recruiting
- Phase
- Phase 2
- People taking part
- 20 people, planned
- Started
- 13 Feb 2026
- Expected to end
- May 2028
- Type of study
- Interventional
- Treatments tested
- CBD
- Record updated
- 16 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a spinal cord injury above the lowest part of the spine who leak urine. Participants take Epidiolex (purified CBD) for 90 days.
- Age
- Over 18 years.
- Sex
- All sexes can join.
- Disease stage
- Spinal cord injury above the sacral level (supra-sacral), from any cause. At least 2 episodes of urine leakage per day, outside of spinal shock.
- Earlier treatment
- People who have had Botox injected into the bladder cannot join.
Main reasons for not taking part
- Botox injected into the bladder in the past
- Taking more than 15 mg of Oxybutynin per dose, or a similar dose of another anticholinergic bladder medicine
- Cannabis use outside the study, checked by a urine drug test after a 1-month break if past use is reported
- A thought or mood disorder other than depression
- Not English-speaking
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- >18 years of age
- History of supra-sacral spinal cord injury of any mechanism
- Urinary incontinence with ≥2 episodes of urinary incontinence per day (outside of spinal shock)
- Willingness to participate in drug intervention trial
- English-speaking (able to provide consent and complete questionnaires)
Who cannot take part
- Actively taking >15 mg of Oxybutynin single dose or equivalent dose of alternative anticholinergic medication for bladder symptoms
- Use of Cannabis (any form) outside of study as determined by urine drug screen after washout period of 1 month if prior Cannabis use reported
- History of intravesical Botox
- Thought or mood disorder aside from depression
Where in United States
- University of Wisconsin - MadisonMadison, United StatesContact: Maria FloryTaking people
About the trial
What the trial wants to find out
The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI).
Read full original descriptionShow less
Participants will take Epidiolex (purified CBD) for 90 days
The group in the trial
- CBD for urinary incontinenceTreatment being tested
Participants will take CBD for 90 days
Treatment: CBD
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Cannabinoid Modulation for Neurogenic Lower Urinary Tract Dysfunction in Spinal Cord Injury
- Plain-language title
- Cannabidiol for bladder leakage after a recent spinal cord injuryGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 16 September 2026