Imaging heart artery plaque and blood flow in people with narrowed coronary arteries
Compares artery imaging and blood flow measures in adults with moderately narrowed heart arteries.
Key facts
- Who runs it
- Medical University of Warsaw
- Where
- Warsaw, PolandSee the site
- Trial code
- Registry title
- Vessel Imaging Using Optical Coherence Tomography for Plaque Morphology and Vessel Fractional Flow Reserve
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 20 Sept 2020
- Expected to end
- 31 Jan 2029
- Type of study
- Observational
- Treatments tested
- vessel Fractional Flow Reserve
- Record updated
- 25 February 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with chronic coronary syndrome and an intermediate narrowing (40-80%) of a heart artery, to compare artery imaging (OCT) with a flow measurement (vFFR).
- Age
- 18 years or older
- Sex
- Women and men can join.
- Disease stage
- Chronic coronary syndrome, with chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or a positive ischemia test (exercise test, SPECT). Intermediate narrowing of 40-80% of a heart artery, judged visually on the coronary angiogram.
Main reasons for not taking part
- Acute coronary syndrome
- Proximal left main lesion or ostial right coronary artery lesion
- Bypass of the vessel being assessed
- Heart failure in NYHA class IV, or unstable blood circulation (hemodynamic instability)
- Pregnancy, acute renal insufficiency, or contraindications for adenosine
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- 18 years or older
- Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT)
- Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography and OCT examination The patient is willing to participate in the study and has provided a written informed consent
Who cannot take part
- Acute coronary syndrome
- Heart insufficiency in New York Heart Association (NYHA) class IV scale
- Acute renal insufficiency
- Proximal left main lesion
- Ostial right coronary artery lesion
- Bypass of the assessed vessel
- Contraindications for adenosine administration
- Hemodynamic instability
- Pregnancy
Where in Poland
- 1st Department and Clinic of Cardiology, Medical University of WarsawWarsaw, PolandContact: Mariusz Tomaniak, MD, PhD, Assoc. Prof.Taking people
About the trial
What the trial wants to find out
The aim of this prospective, investigator-initiated study is to evaluate the diagnostic accuracy and correlations between mopphometric indices: luminal and qualitative parameters assessed by optical coherence tomography (OCT) including minimal lumen area, plaque type, presence of thin cap fibroatheroma and a functional index - angiography based vessel fractional flow reserve (vFFR) among patients with chronic coronary syndrome identified with intermediate grade coronary stenosis.
The group in the trial
- Patients undergoing coronary angiogram in chronic coronary syndrome with intermediate stenosis.
Patients undergoing coronary angiogram due to chronic coronary syndrome with intermediate grade coronary stenosis.
Treatment: vessel Fractional Flow Reserve
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Vessel Imaging Using Optical Coherence Tomography for Plaque Morphology and Vessel Fractional Flow Reserve
- Plain-language title
- Imaging heart artery plaque and blood flow in people with narrowed coronary arteriesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 25 February 2025