Checking bowel blood flow with a glowing dye during colorectal cancer surgery
Tests glowing dye imaging to prevent bowel leaks after colorectal cancer surgery.
Plain-language title generated from the registry record
Registry title: The Use of Indocyanine Green Near-infrared Fluorescence for Bowel Perfusion Quantitative Assessment in Order to Prevent Anastomotic Leakage in Colorectal Surgery
Key facts
- Where
- Vsevolozhsk District, RussiaSee the site
- Phase
- Phase 3
Where in Russia
- BELOOSTROV Clinic of High TechnologiesVsevolozhsk District, RussiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vadim Kuznetsov
- Trial code
- NCT06845306
- Record updated
- 25 February 2025
- Original description
Anastomotic leakage (AL) is a serious complication after surgery for colon cancer, leading to a significant increase in mortality.Intraoperative fluorescence imaging using indocyanine green has proven to be a feasible and reproducible technique for real-time perfusion assessment.Read full original descriptionShow less
Indocyanine Green Near-infrared Fluorescence Bowel Perfusion Quantitative Assessment to Prevent Anastomotic Leakage in Colorectal Surgery: a Multicentre, Randomised, Controlled Study
Anastomotic leakage (AL) is a serious complication after surgery for colon cancer, leading to a significant increase in mortality.Intraoperative fluorescence imaging using indocyanine green has proven to be a feasible and reproducible technique for real-time perfusion assessment.
An increasing number of studies are being published on the use of indocyanine green (ICG) fluorescence imaging in colorectal cancer surgery, showing promising results.
Therefore, we propose conducting a multicenter, randomized controlled trial to investigate the potential use of quantitative assessment of near-infrared fluorescence imaging with indocyanine green (ICG) to prevent anastomotic leaks during colorectal surgery.
Inclusion: Patients aged over 18 years old; ECOG status 0-2; Written informed consent; histologically confirmed neoplasms malignant of the colon (caecum, ascending, transverse, descending, sigmoid); Scheduled for colorectal resection with primary anastomosis.
Exclusion: Medical contraindications for surgical treatment; Colon obstruction, perforation or bleeding complicating the tumor; Known allergy or history of adverse reaction to ICG, iodine or iodine dyes; Pregnancy or breast feeding.