Testing two strength training loads on blood pressure in aging women
Tests two strength training loads on blood pressure in women aged 50 to 70.
Plain-language title generated from the registry record
Registry title: Impact of Resistance Training Intensity on Blood Pressure
Key facts
- Where
- Sherbrooke, CanadaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 70 years old?
Source: NCT06845514, who can take part
Where in Canada
- Research Center on AgingSherbrooke, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Université de Sherbrooke
- Trial code
- NCT06845514
- Record updated
- 9 September 2025
- Original description
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in reserve; RIR) on post-exercise and ambulatory blood pressure in aging females.Read full original descriptionShow less
High Blood Pressure and Effect of Acute Resistance Training: Influence of Different Load Intensities on Postexercise Hypotension and Ambulatory Blood Pressure in Aging Females
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in reserve; RIR) on post-exercise and ambulatory blood pressure in aging females.
The main questions it aims to answer are:
* to examine the acute effects of low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise with a standardized high effort intensity on post-exercise hypotension and ambulatory blood pressure responses in aging females; * deepen the understanding of the mechanisms underlying acute reductions in blood pressure in response to resistance exercise performed at different load intensities. To this end, autonomic activity will be estimated alongside the measurement of central arterial compliance (i.e., carotid artery), and serum biomarkers of endothelial function; * document the affective valence and enjoyment associated with low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise when performed at a high perceived effort.
Researchers will compare the effect of: 1) a low load (LL-RE) intensity protocol consisting of 3 sets of each exercise at 50% 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 2) high load (HL-RE) intensity protocol consisting of 3 sets of each exercise at 80% of 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 3) and a control condition (CON) consisting of a standardized non-fatiguing cognitive task.
Participants will participate in:
* A preliminary assessment visit; * Two familiarization visits to validate the exercise prescriptions; * Three experimental visits (CON, LL-RE, HL-RE).
Inclusion: aged 50 to 70 years; absence of menstruation for 12 consecutive months; normal-high resting blood pressure (120 ≤ Systolic ≤ 139 mmHg and 80 ≤ Diastolic ≤ 89 mmHg) or stage 1 hypertension (140 ≤ Systolic ≤ 159 mmHg or 90 < Diastolic ≤ 99 mmHg); physically inactive (< 150 minutes of structured aerobic physical activity per week); and not engaging in regular resistance exercise (≥ 2 sessions per week) for more than 3 months during the year.
Exclusion: scheduled surgery during the study; and initiation of hormonal replacement therapy (< 4 months) known to affect blood pressure; unstable hypertension (≥ 160/100 mmHg); diagnosis of type 2 diabetes; orthopedic limitations or other contraindications to resistance exercise; cardiovascular event in the past 6 months or sequelae preventing exercise.