Testing two strength training loads on blood pressure in aging women
Tests two strength training loads on blood pressure in women aged 50 to 70.
Key facts
- Who runs it
- Université de Sherbrooke
- Where
- Sherbrooke, CanadaSee the site
- Trial code
- Registry title
- Impact of Resistance Training Intensity on Blood Pressure
- Status
- Recruiting
- People taking part
- 36 people, planned
- Started
- 8 Jul 2025
- Expected to end
- Dec 2028
- Type of study
- Interventional, 3 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- Condition LL-RE
- Control
- Condition HL-RE
- Record updated
- 9 September 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 50 to 70 who have gone through menopause, have raised blood pressure and are physically inactive.
- Age
- 50 to 70 years
- Sex
- Women only
- Disease stage
- Normal-high blood pressure (120 to 139 systolic and 80 to 89 diastolic mmHg) or stage 1 high blood pressure (140 to 159 systolic or 90 to 99 diastolic mmHg). No period for 12 months in a row.
- Earlier treatment
- Not doing regular resistance exercise (2 or more sessions per week) for more than 3 months during the year. Not on hormone replacement therapy started less than 4 months ago.
Main reasons for not taking part
- Bone, joint or other problems that make resistance exercise unsafe
- Surgery planned during the study
- Unstable high blood pressure (160/100 mmHg or higher)
- Type 2 diabetes
- Heart or blood vessel event in the past 6 months
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- aged 50 to 70 years
- absence of menstruation for 12 consecutive months
- normal-high resting blood pressure (120 ≤ Systolic ≤ 139 mmHg and 80 ≤ Diastolic ≤ 89 mmHg) or stage 1 hypertension (140 ≤ Systolic ≤ 159 mmHg or 90 < Diastolic ≤ 99 mmHg)
- physically inactive (< 150 minutes of structured aerobic physical activity per week)
- and not engaging in regular resistance exercise (≥ 2 sessions per week) for more than 3 months during the year
Who cannot take part
- scheduled surgery during the study
- and initiation of hormonal replacement therapy (< 4 months) known to affect blood pressure
- unstable hypertension (≥ 160/100 mmHg)
- diagnosis of type 2 diabetes
- orthopedic limitations or other contraindications to resistance exercise
- cardiovascular event in the past 6 months or sequelae preventing exercise
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 70 years old?
Where in Canada
- Research Center on AgingSherbrooke, CanadaContact: Eléonor Riesco, Ph.D.Taking people
About the trial
What the trial wants to find out
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in reserve; RIR) on post-exercise and ambulatory blood pressure in aging females.
Read full original descriptionShow less
The main questions it aims to answer are:
* to examine the acute effects of low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise with a standardized high effort intensity on post-exercise hypotension and ambulatory blood pressure responses in aging females; * deepen the understanding of the mechanisms underlying acute reductions in blood pressure in response to resistance exercise performed at different load intensities. To this end, autonomic activity will be estimated alongside the measurement of central arterial compliance (i.e., carotid artery), and serum biomarkers of endothelial function; * document the affective valence and enjoyment associated with low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise when performed at a high perceived effort.
Researchers will compare the effect of: 1) a low load (LL-RE) intensity protocol consisting of 3 sets of each exercise at 50% 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 2) high load (HL-RE) intensity protocol consisting of 3 sets of each exercise at 80% of 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 3) and a control condition (CON) consisting of a standardized non-fatiguing cognitive task.
Participants will participate in:
* A preliminary assessment visit; * Two familiarization visits to validate the exercise prescriptions; * Three experimental visits (CON, LL-RE, HL-RE).
The 3 groups in the trial
- Condition LL-RETreatment being tested
Low-load resistance exercise
- Condition HL-RETreatment being tested
High-load resistance exercise
- Condition CONSham treatment, for comparison
Control condition
Treatment: Control
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- High Blood Pressure and Effect of Acute Resistance Training: Influence of Different Load Intensities on Postexercise Hypotension and Ambulatory Blood Pressure in Aging Females
- Plain-language title
- Testing two strength training loads on blood pressure in aging womenGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06845514, who can take part
- Record updated
- 9 September 2025