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Studies how uterine fluid is absorbed in early pregnancy

Observes fluid absorption in the uterus of adults with endometriosis early in pregnancy.

Plain-language title generated from the registry record
Registry title: Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Key facts

Where
Athens, Baltimore, and Piscataway, United StatesSee the 3 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 45 years old?

Source: NCT06847685, who can take part

Where in United States

  • University of GeorgiaAthens, United StatesNot yet recruiting
  • Johns Hopkins HospitalBaltimore, United StatesTaking people
  • Rutgers UniversityPiscataway, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Johns Hopkins University
Trial code
NCT06847685
Record updated
9 March 2026
Original description
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancyRead full original descriptionShow less

Mechanisms of Uterine Fluid Absorption During Early Pregnancy

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy

Inclusion: Subject must be a healthy woman between the ages of 18 and 45 years; Women with diagnosed endometriosis or infertility (cases); Women without a diagnosis of endometriosis or infertility (controls); Subject must have regular menstrual cycles; Subject must have a body mass index (BMI) between 18 and 40; Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum; Subject must be able to understand and provide consent to procedures and use/disclosure of protected health information; No history of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, hepatitis B, and HIV; For IVF study subjects, a minimum endometrial thickness of 7mm at the time of sample collection.

Exclusion: Study subjects with endometrial cancer; Study subjects with a history of endometrial ablation; Study subjects with undiagnosed uterine bleeding; Women with reproductive diseases that affect the endometrium (such as fibroids or uterine polyps that distort endometrial cavity); Pregnant women; Study subjects with an intrauterine device (IUD).

ClinicalTrials.gov NCT06847685