Tests a flexible scope procedure to monitor upper tract urothelial carcinoma after surgery
Tests a flexible ureteroscopy under local anaesthesia in adults treated for upper tract urothelial carcinoma.
Plain-language title generated from the registry record
Registry title: Ambulatory Flexible URS for UTUC Surveillance
Key facts
- Where
- Hong Kong, Hong KongSee the 2 sites
- Phase
- Phase 1
Where in Hong Kong
- Prince of Wales HospitalHong Kong, Hong KongTaking people
- The Chinese University of Hong KongHong Kong, Hong KongNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chinese University of Hong Kong
- Trial code
- NCT06848868
- Record updated
- 15 September 2025
- Original description
This is a a prospective single-arm pilot study to investigate the safety and feasibility of flexible ureteroscopy under local anaesthesia. All consecutive patients who have undergone kidney-sparing surgery for managing upper tract urothelial carcinoma will be screened for study eligibility. The primary outcome is the procedural technical success rate. Secondary outcomes include the 30-day complication rate following flexible ureteroscopy, readmission rates, cost analysis, and patient-reported outcomes. Ureterorenoscopy will be conducted in the recruited patients under local anaesthesia in the ambulatory urology centre. Procedural details, technical success rates, adverse events and patient reported outcomes will be documented. The anticipated risks of this intervention are not expected to exceed those associated with the standard of care, that is ureterorenoscopy under anaesthesia. This pilot study aims to recruit a total of 10 subjects to assess the safety and feasibility of flexible ureterorenoscopy in an ambulatory care setting.Read full original descriptionShow less
Flexible Ureterorenoscopy for Surveillance of Upper Tract Urothelial Carcinoma-A Pilot Study
This is a a prospective single-arm pilot study to investigate the safety and feasibility of flexible ureteroscopy under local anaesthesia. All consecutive patients who have undergone kidney-sparing surgery for managing upper tract urothelial carcinoma will be screened for study eligibility. The primary outcome is the procedural technical success rate. Secondary outcomes include the 30-day complication rate following flexible ureteroscopy, readmission rates, cost analysis, and patient-reported outcomes. Ureterorenoscopy will be conducted in the recruited patients under local anaesthesia in the ambulatory urology centre. Procedural details, technical success rates, adverse events and patient reported outcomes will be documented. The anticipated risks of this intervention are not expected to exceed those associated with the standard of care, that is ureterorenoscopy under anaesthesia. This pilot study aims to recruit a total of 10 subjects to assess the safety and feasibility of flexible ureterorenoscopy in an ambulatory care setting.
Inclusion: Aged 18 years or older; Capable of giving informed consent; Having undergone an kidney-sparing surgery (endoscopic operation or segmental ureterectomy).
Exclusion: Allergy to transurethral lidocaine jelly; On anticoagulation or anti-platelet medication with contraindications for cessation prior to the procedure; Structural abnormalities in the upper urinary tract on the intended side of examination.