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Predicting Outcomes in Critically Ill Brain Patients Receiving Tube Feeding

Studies a prediction model using blood markers in adults with acute stroke or brain infection.

Plain-language title generated from the registry record
Registry title: Inflammatory and Metabolic Prognostic Assessment in Critically Ill Neurological Patients

Key facts

Where
Beijing, Chifeng, Guiyang, Hohhot, Jilin City, Jinan, Kunming, Lanzhou, Liaocheng, Shijiazhuang, Suzhou, Taiyuan, Tangshan, Yinchuan, and Zunyi, ChinaSee the 19 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT06849011, who can take part

Where in China

  • Beijing Hui People's HospitalBeijing, ChinaNo longer taking part
  • The Ninth Medical Center of Chinese PLA General HospitalBeijing, ChinaNo longer taking part
  • Xuanwu Hospital, Capital Medical UniversityBeijing, ChinaNo longer taking part
  • You'anmen HospitalBeijing, ChinaNo longer taking part
  • Chifeng Municipal HospitalChifeng, ChinaNo longer taking part
  • Guizhou Provincial People's HospitalGuiyang, ChinaNo longer taking part
  • Inner Mongolia Autonomous Region People's HospitalHohhot, ChinaNo longer taking part
  • The First Hospital of Jilin UniversityJilin City, ChinaNo longer taking part
  • Qilu Hospital of Shandong UniversityJinan, ChinaNo longer taking part
  • The 960th Hospital of Joint Logistics Support Force of Chinese PLAJinan, ChinaNo longer taking part
  • The First People's Hospital of Yunnan ProvinceKunming, ChinaNo longer taking part
  • The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhou, ChinaNo longer taking part
  • Liaocheng People's HospitalLiaocheng, ChinaNo longer taking part
  • The First Hospital of Hebei Medical UniversityShijiazhuang, ChinaNo longer taking part
  • The Second Affiliated Hospital of Suzhou UniversitySuzhou, ChinaNo longer taking part
  • The Second Hospital of Shanxi Medical UniversityTaiyuan, ChinaNo longer taking part
  • Tangshan People's HospitalTangshan, ChinaNo longer taking part
  • General Hospital of Ningxia Medical UniversityYinchuan, ChinaNo longer taking part
  • Affiliated Hospital of Zunyi Medical UniversityZunyi, ChinaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Yan Zhang
Trial code
NCT06849011
Record updated
27 February 2025
Original description
The study aims to develop and validate a prognostic prediction model for adverse outcomes in neurocritical patients receiving enteral nutrition based on key inflammatory and metabolic markers. This model will serve as a clinical tool to help physicians identify high-risk patients and guide individualized nutritional support strategies.Read full original descriptionShow less

Development and Validation of a Prognostic Prediction Model for Adverse Outcomes in Neurocritical Patients Receiving Enteral Nutrition Based on Key Inflammatory and Metabolic Markers

The study aims to develop and validate a prognostic prediction model for adverse outcomes in neurocritical patients receiving enteral nutrition based on key inflammatory and metabolic markers. This model will serve as a clinical tool to help physicians identify high-risk patients and guide individualized nutritional support strategies.

Inclusion: Age between 18 and 80 years, no gender restrictions; Within 7 days of disease onset and expected NICU stay of at least 7 days; Eligible for enrollment within 24 hours of NICU admission, with enteral nutrition (EN) initiated and continued for at least 7 days; Non-traumatic severe brain injury patients (including cerebrovascular disease and encephalitis) with a Glasgow Coma Scale (GCS) score ≤12; NRS 2002 score ≥3; Kuwata drinking test ≥ grade 3; Acute Gastrointestinal Injury (AGI) grade 1 or 2; Signed informed consent obtained from the patient or their legal representative.

Exclusion: Severe malnutrition prior to admission, defined as BMI < 16 kg/m²; Receiving hypothermia treatment or core body temperature < 36°C; End-stage disease with an expected survival time of < 48 hours, or severe dysfunction of the heart, lungs, or other vital organs, leading to hemodynamic instability; Malignant tumors; Pregnant or lactating women.

ClinicalTrials.gov NCT06849011