Enrolling by invitationNo phase

Comparing Two Diets for Children with Autism and Stomach Symptoms

Compares a gluten-free casein-free diet with the Feingold diet in children with autism.

Key facts

Who runs it: Aydin Adnan Menderes University
Where: Aydin, TürkiyeSee the site
Trial code: NCT06852027
Registry title: Different Dietary Practices in Children with Autism Spectrum Disorder
Status: Enrolling by invitation
People taking part: 45 people, planned
Started: Feb 2025
Planned end: Jul 2026
Type of study: Interventional, 3 groupsOne group gets no study treatment, for comparison.
Treatments tested: Different Dietary Practices
Record updated: 28 February 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children with autism aged 3 to 10 who are registered at Efeler Autism Life Center in Aydın province. It compares two diets.

Age: 3 to 10 years
Sex: Boys and girls can both join.
Disease stage: Children with autism spectrum disorder. For the gluten-free casein-free diet, children must have stomach and gut complaints.
Earlier treatment: Children must not have followed a gluten-free, gluten-free casein-free or lactose-free diet before (for that diet). They must not have followed the Feingold diet before (for that diet).

Main reasons for not taking part

Celiac disease or lactose intolerance (for the gluten-free casein-free diet)
Diagnosis of attention deficit and hyperactivity disorder (for the Feingold diet)
Any food allergy (for the Feingold diet)
Any chronic disease or any psychiatric disease
Breastfed child, or not following the diet or not answering the survey

The registry criteria, word for word

Show all 10 criteriaShow less

Who can take part

The criteria for inclusion for the gluten-free-casein-free diet are as follows:
Not having diseases such as celiac, lactose intolerance
Not having previously applied a gluten-free diet, gluten-free casein-free diet, lactose-free diet
Having gastrointestinal complaints; The criteria for inclusion for the Feingold Diet are as follows:
Not having been diagnosed with attention deficit and hyperactivity disorder
Not having previously taken the Feingold diet
Not having any food allergies

Who cannot take part

The patient has any chronic disease
The patient has any psychiatric disease
The patient is breastfed

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 3 and 10 years old?

Where in Türkiye

Aydin province Efeler Autism Life CenterAydin, TürkiyeNo longer taking part

About the trial

What the trial wants to find out

The aim of this study is to investigate the effects of gluten-free casein-free diet and feingold diet on gastrointestinal system (GI) symptoms , eating behavior and quality of life in children with autism spectrum disorder. Research questions are below:

Read full original descriptionShow less

Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on GI symptoms? Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on eating behavior? Is there a difference in the effects of a gluten-free-casein-free diet and the Feingold Diet on quality of life?

The 3 groups in the trial

Gluten-Free-Casein-Free DietTreatment being tested
The Gluten-free Casein-free diet is one of the most researched diets for Autism Spectrum Disorder. This diet is based on the elimination of foods containing gluten and casein. In this arm, children between the ages of 3 and 10 will be subjected to a Gluten-free-Casein-free diet for 12 weeks. Children will be controlled for compliance with the diet every two weeks.
Treatment: Different Dietary Practices
Feingold DietTreatment being tested
The Feingold Diet was originally developed for Attention Deficit and Hyperactivity Disorder, it is thought to be effective in symptomatic treatment due to enzyme deficiency in children with Autism Spectrum Disorder, but there are not enough studies on it. The Feingold Diet is one of the most researched diets for Autism Spectrum Disorder. This diet is based on the elimination of foods containing gluten and casein. In this arm, children between the ages of 3 and 10 will be subjected to a the Feingold Diet diet for 12 weeks. Children will be controlled for compliance with the diet every two weeks.
Treatment: Different Dietary Practices
ControlNo study treatment, for comparison
the arm receives no intervention during the study. (CONTROL GROUP). Children in this group will be monitored every 2 weeks for 12 weeks.