Training Brain Activity With Neurofeedback After Stroke
Tests whether stroke patients with cognitive problems can learn to control brain activity.
Plain-language title generated from the registry record
Registry title: Training Cognition With Neurofeedback After Stroke
Key facts
- Where
- Bordeaux, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06852209, who can take part
Where in France
- CHU de BordeauxBordeaux, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Bordeaux
- Trial code
- NCT06852209
- Record updated
- 2 April 2025
- Original description
Post-stroke cognitive impairment (PSCI) is a common source of invisible disability. The actual techniques of cognitive remediation have been reported to have only a small effect, justifying the need to foster research in this field. Real-time functional MRI neurofeedack (rt-fMRI NF) is a procedure of brain-machine interface supporting self-regulation of brain activity, with promising results in the treatment of mental disorders. The main objective of the study is to evaluate in a pilot study, the ability of stroke patients to learn to self-regulate their brain activity in a priviledged direction, using rt-fMRI NFRead full original descriptionShow less
Cognitive Impairment Mechanisms and Training With Real Time-functional MRI Neurofeedback After Stroke
Post-stroke cognitive impairment (PSCI) is a common source of invisible disability. The actual techniques of cognitive remediation have been reported to have only a small effect, justifying the need to foster research in this field. Real-time functional MRI neurofeedack (rt-fMRI NF) is a procedure of brain-machine interface supporting self-regulation of brain activity, with promising results in the treatment of mental disorders. The main objective of the study is to evaluate in a pilot study, the ability of stroke patients to learn to self-regulate their brain activity in a priviledged direction, using rt-fMRI NF
Inclusion: Men or women; Right handed; 18 ≤ years old < 75; first-ever ischemic stroke on brain MRI in the past 3 to 6 months ; Persisting cognitive complaint 3 months after the ischemic stroke, proved by a MoCA score ≤ 26 (if educational level ≥ 12 years, or ≤ 25 if educational level < 12 years), and involving at least one of the following cognitive domains : executive functions, attention, and processing speed ; Ischemic stroke located in the territory of the middle cerebral artery and /or basal ganglia/thalamus ; NIHSS ≤ 5, without aphasia or severe visual disability empeding the understanding of the instructions, the neurofeedback task achievement, and/or the neuropsychological assessment ; No prestroke disability defined by a modified Rankin Scale ≤ 2 ; For women of childbearing potential, use of effective contraception and negative pregnancy test; Written informed consent by the patient; Coverage by the French Social Insurance.
Exclusion: Previous cognitive impairment ; Current use of psychotropic medication ; History of psychiatric disorder ; Chronic disease empeding the follow-up of the subject during the lenght of the study ; MRI contraindication ; Pregnancy or breastfeeding ; Non fluently-French speakers ; Patient under legal protection; Patient unable of giving personal consent; Emergency situation; 1st MRI incomplete, not performed or not analyzable.