Dye Versus Stents to Find Urine Tubes During Endometriosis Surgery
Tests a dye instead of plastic stents to locate urine tubes in women with endometriosis.
Plain-language title generated from the registry record
Registry title: Ureteric Identification Using Indocyanine Green Dye Versus Conventional Ureteric Stenting to Reduce Post-operative Pain and Surgical Morbidity During Endometriosis Surgery
Key facts
- Where
- Stoke-on-Trent, United KingdomSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT06852248, who can take part
Where in United Kingdom
- University Hospitals of North Midlands NHS TrustStoke-on-Trent, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospitals of North Midlands NHS Trust
- Trial code
- NCT06852248
- Record updated
- 3 September 2025
- Original description
Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis. Symptoms vary but can include intense pelvic pain and infertility.Read full original descriptionShow less
Ureteric Identification Using Indocyanine Green Dye Versus Conventional Ureteric Stenting to Reduce Post-operative Pain and Surgical Morbidity During Endometriosis Surgery: A Pilot Trial (ICE Trial)
Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis. Symptoms vary but can include intense pelvic pain and infertility.
Endometriosis that is very deep and painful may need surgery, which risks damage to the tubes that drain urine from the kidneys to the bladder (ureters). To reduce this risk, surgeons may put tiny plastic tubes called "stents" inside the ureters. These stents can stay for up-to 4 weeks following surgery but can cause severe pain and blood in the urine. Squirting a dye into the ureters, rather than using stents, may cause less pain for women after surgery whilst not making the removal of endometriosis worse, the operation take longer, or increasing the rates of complications (such as bleeding or damage to internal organs). Before a full clinical study can be run, the investigators need to understand whether this is possible, by doing a feasibility study
Inclusion: Women aged 18 to 50 years; Scheduled for laparoscopic or robotic-assisted surgical excision of deep endometriosis (DE) where ureteric stenting is planned; Willing and able to provide consent for participation in the study.
Exclusion: History of ureteric injury from prior surgery or trauma; Suspicion or confirmation of malignancy; Medically unfit for surgery due to the following conditions:; Uncontrolled diabetes mellitus; Severe Chronic Obstructive Pulmonary Disease (COPD); Hypertrophic cardiomyopathy or significant cardiac conditions (e.g., recent myocardial infarction, aortic stenosis); History of stroke or severe kyphoscoliosis; Uncontrolled hypertension; Confirmed or suspected pregnancy at the time of enrolment; Body mass index (BMI): BMI greater than 45.