Tests NKG2D CAR-NK cells with a PD-1 antibody for anaplastic thyroid cancer
Tests immune cells with a PD-1 antibody in adults with anaplastic thyroid cancer.
Plain-language title generated from the registry record
Registry title: Clinical Study of NKG2D CAR-NK Combined with PD-1 Monoclonal Antibody in the Treatment of ATC
Key facts
- Where
- Hangzhou, ChinaSee the site
- Phase
- Phase 1/2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06856278, who can take part
Where in China
- Zhejiang Provincial People's HospitalHangzhou, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zhejiang Provincial People's Hospital
- Trial code
- NCT06856278
- Record updated
- 4 March 2025
- Original description
The patients with anaplastic thyroid cancer were treated with CAR-NK immune cells combined with PD-1 monoclonal antibody, and the safety and tolerability of the patients were observed and evaluated.Read full original descriptionShow less
Clinical Exploratory Study of NKG2D CAR-NK Combined with PD-1 Monoclonal Antibody in the Treatment of Anaplastic Thyroid Cancer (ATC)
The patients with anaplastic thyroid cancer were treated with CAR-NK immune cells combined with PD-1 monoclonal antibody, and the safety and tolerability of the patients were observed and evaluated.
Inclusion: Age 18-75 years (including boundary values), male or female; Be diagnosed with anaplastic thyroid cancer histopathologically with a measurable lesion≥1cm; Liver and kidney function is good, and can tolerate treatment; Be able to cooperate with the completion of treatment and follow-up work; No other systemic diseases, including other malignancies.
Exclusion: Immune system diseases; Diseases of the blood system; Mental system diseases; Interstitial pneumonia, lung disease, etc; Failure to follow rules of this study; Need to breastfeed the baby or have fertility needs；.