Testing TUNE In, a social and emotional program for adults with autism
Tests a social skills program called TUNE In in adults with autism spectrum disorder.
Plain-language title generated from the registry record
Registry title: Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
Key facts
- Where
- Philadelphia, United StatesSee the site
Where in United States
- Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of PennsylvaniaPhiladelphia, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Pennsylvania
- Trial code
- NCT06859918
- Record updated
- 13 March 2026
- Original description
The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.Read full original descriptionShow less
ASPE Subproject - Training to Understand and Navigate Emotions and Interactions (TUNE In)
The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.
The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings.
The Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.
Inclusion: 18 years of age or older; Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and/or by the clinical and developmental information gathered from a phone screen; Be willing to complete screening surveys (outcome measures); Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60.
Exclusion: Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months; A history of intellectual disability or low Shipley-2 score; Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months.