Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
Key facts
- Who runs it
- University Hospitals Cleveland Medical Center
- Where
- Cleveland, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 170 people, planned
- Started
- 5 May 2025
- Planned end
- 15 Nov 2026
- Type of study
- Observational
- Treatments tested
- Blood Draw
- Record updated
- 4 September 2026
Who can take part
- Age
- 21 years to 79 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- 1. Age range: 21-79
- 2. Patients undergoing elective surgery at UHCMC with planned ICU admission
- 3. Patients undergoing elective surgery at UHCMC with expected in-hospital admission for three or more days
- 4. Only patients who consume alcoholic beverages on a regular basis
Who cannot take part
- 2. Subjects who have received a blood transfusion within the past month before surgery
- 1. Patients undergoing same day outpatient surgeries or expected to be admitted less than three days post-operatively
- 3. Pregnant subjects
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 79 years old?
Where in United States
- University HospitalCleveland, United StatesContact: Ayse Ulucay, MDTaking people
About the trial
What the trial wants to find out
This study aims to see if there's a link between a substance called phosphatidylethanol (PEth) and how patients who have surgery at University Hospitals do after surgery. PEth levels reflect the amount of alcohol use by someone over the past few weeks. This study is checking PEth levels on all patients who are planned to stay in the hospital for three or more days after surgery regardless if they drink alcohol. Specifically, it will look at if PEth levels are connected to problems that might come up during and after surgery, like confusion, lung or heart issues, needing blood transfusions, infections, unexpected intensive care unit (ICU) stays, and longer hospital stays. While there are reports of moderate alcohol consumption being good for the heart, there are other data that alcohol consumption can be harmful. Since there's not much information on how drinking alcohol affects health outcomes during and after surgery, especially for patients who are planned to be admitted to the hospital ward or ICU after surgery, this study will hopefully see if PEth levels before surgery can predict how patients do after the surgery.
Read full original descriptionShow less
The inclusion criteria to only include patients who consume alcoholic beverages was an IRB approved modification after already recruiting 1/3 of patients.
The group in the trial
- Patients undergoing elective surgery at UHCMC.
Patients will have a single blood sample sent for PEth testing.
Treatment: Blood Draw
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT06864819, who can take part
- Record updated
- 4 September 2026