NCT06865326Recruiting
Early Detection of CTEPH in Patients After APE
Early Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients After Acute Pulmonary Embolism
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 2 Dec 2024
- Start date
- 7 Mar 2025
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Institute of Health Information and Statistics of the Czech Republic
- NCT number
- NCT06865326
What you commit to
- Study type: Observational
- Planned participants: 500
- From 7 Mar 2025 to the primary completion date, 31 Dec 2027
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Not agreeing to participate in the project
- Contraindications to treatment
Who the study is looking for
- Age over 18 years
- Signed consent to participate in the project and GDPR
- Patients with an episode of acute pulmonary embolism in the last 3-12 months, with ongoing anticoagulation therapy:
- Patients with new-onset and ongoing or progressive dyspnea (min. NYHA II) after a pulmonary embolism episode or worsening of dyspnea after a pulmonary embolism episode compared to the status before the episode (at least 1 HYHA grade) or
- Asymptomatic patients after a pulmonary embolism episode and at least one of the following risk factors:
- ECHO evidence of severe PH at diagnosis of PE (PASP \>60 mmHg)
- Antiphospholipid syndrome with triple positivity (presence of lupus anticoagulans + anti-beta-2-glycoprotein I (B2GPI) antibodies + anticardiolipin)
- Infected permanent venous inlets and cardiac pacing/defibrillation intravascular systems
- Presence of ventriculoatrial shunt for treatment of hydrocephalus
- Nonspecific intestinal inflammation (ulcerative colitis, Crohn's disease)
- History of splenectomy
- Myeloproliferative disorders
- Chronic osteomyelitis
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brno University Hospital Coordinator of this site? Confirm its status | Brno | Czechia | Recruiting |
| Havlíčkův Brod Hospital Coordinator of this site? Confirm its status | Havlíčkův Brod | Czechia | Recruiting |
| University Hospital Hradec Kralove Coordinator of this site? Confirm its status | Hradec Králové | Czechia | Recruiting |
| Jihlava Hospital Coordinator of this site? Confirm its status | Jihlava | Czechia | Recruiting |
| Náchod Hospital Coordinator of this site? Confirm its status | Náchod | Czechia | Recruiting |
| University Hospital Olomouc Coordinator of this site? Confirm its status | Olomouc | Czechia | Recruiting |
| University Hospital Ostrava Coordinator of this site? Confirm its status | Ostrava | Czechia | Recruiting |
| Pardubice Hospital Coordinator of this site? Confirm its status | Pardubice | Czechia | Recruiting |
| Rychnov nad Kněžnou Hospital Coordinator of this site? Confirm its status | Rychnov nad Kněžnou | Czechia | Recruiting |
| Tábor Hospital Coordinator of this site? Confirm its status | Tábor | Czechia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.