Study on Blood Pressure Variability and Frailty in the Older People
Key facts
- Where
- Milan, ItalySee the site
Where in Italy
- Istituto Auxologico Italiano IRCCSMilan, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituto Auxologico Italiano
- Trial code
- NCT06868069
- Record updated
- 30 March 2026
- Original description
Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) <90 mmHg (or two episodes of daytime SBP <90 mmHg, if mean 24 h SBP is <125 mmHg) detected at Ambulatory Blood Pressure Monitoring (ABPM) is associated with adverse events at follow up (death, hospitalization, falls, emergency room admission for uncontrolled hypertension, major cardiovascular events)Read full original descriptionShow less
Study on Blood Pressure Variability and Frailty in the Older People: the HypoPHrail Study
Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) <90 mmHg (or two episodes of daytime SBP <90 mmHg, if mean 24 h SBP is <125 mmHg) detected at Ambulatory Blood Pressure Monitoring (ABPM) is associated with adverse events at follow up (death, hospitalization, falls, emergency room admission for uncontrolled hypertension, major cardiovascular events)
Inclusion: Age ≥ 75 years; Diagnosis of hypertension according to the criteria of the European Society of Cardiology guidelines [Williams 2018]; Consent of the patient (or legal representative) to participate in the study.
Exclusion: Refusal of the patient or his/her legal representative; Life expectancy of less than 6 months.