Comparing two exercise types and their short-term effects in young women with overweight
Compares high-intensity intervals with moderate continuous exercise in young women with overweight.
Key facts
- Who runs it
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
- Where
- São Paulo, BrazilSee the site
- Trial code
- Registry title
- Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
- Status
- Recruiting
- People taking part
- 15 people, planned
- Started
- 1 Feb 2025
- Expected to end
- 30 Dec 2026
- Type of study
- Interventional, 2 groups
- Treatments tested
- Exercise
- Record updated
- 31 August 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for young women with overweight or obesity. It compares two kinds of exercise sessions.
- Age
- 20 to 45 years
- Sex
- Women only
- Disease stage
- Overweight or obesity, BMI 25-35 kg/m²
Main reasons for not taking part
- Contraceptive use
- Menopause
- Irregular menstrual cycle
- Medical reasons not to do intense physical activity
- Painful joints or taking a ß-blocker
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- women with overwieght or obesity (BMI: 25-35 kg/m²)
Who cannot take part
- contraceptive use
- menopause
- irregular menstrual cycle
- medical contraindications to intense physical activity,
- painful joints,
- taking ß-blocker
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 45 years old?
Where in Brazil
- Laboratório de Fisiologia e Metabolismo Aplicados à Educação FísicaSão Paulo, BrazilContact: JULIANA MONIQUE LINO APARECIDO, PhDTaking people
About the trial
What the trial wants to find out
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear.
Read full original descriptionShow less
This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.
The 2 groups in the trial
- High Intensity Interval ExerciseTreatment being tested
High Intensity Interval Exercise: 5 minutes of WarmUp + 10 x (1 minute at 85% HRmax followed by 1 minute of recovery at a power equivalent to 40% of HRmax)
Treatment: Exercise
- Moderate Intensity Continuous ExerciseTreatment being tested
Moderate Intensity Continuous Exercise: 5 minutes of WarmUp + 35 minutes at 55% HRmax
Treatment: Exercise
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Acute Physiological Responses to Isoenergetic High-Intensity Interval vs. Moderate-Intensity Continuous Exercise in Overweight or Obese Young Females: Focus on Catecholamines, Oxygen Consumption, Lipid Utilization, and Appetite Regulation
- Plain-language title
- Comparing two exercise types and their short-term effects in young women with overweightGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06868862, who can take part
- Record updated
- 31 August 2026