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Spinal Cord Injury Neurorecovery Collaboration

Key facts

Who runs it
University of Melbourne
Where
Australia1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
24 people, planned
Started
1 Mar 2025
Expected to end
31 Dec 2027
Type of study
Interventional
Treatments tested
  • Therapeutic Intermittent Hypoxia (TIH) + Exercise Training (ET)
Record updated
8 August 2025

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 17 criteriaShow less

Other criteria

  • SCINC Inclusion Criteria:
  • Person with SCI; SCINC Exclusion Criteria:
  • Proven contraindication to intervention; RRULI: Appendix 1 (TIH + ET) study-specific inclusion criteria:
  • Adults > 18 years of age
  • Able to independently ventilate
  • Chronic SCI (>1 years post-injury or impairment onset)
  • Tetraplegia (C2-T1 level of injury)
  • Evidence of motor incomplete paralysis in the upper limb below the neurological level of injury
  • Have a documented management plan for their AD if it occurs; RRULI: Appendix 1 (TIH + ET) study-specific exclusion criteria:
  • Pregnancy
  • Medical instability, including current or recent (within the previous 6 weeks) infection or inflammation
  • Current or recent (within the previous 6 weeks) pressure ulcers or cutaneous lesions
  • Poorly controlled diabetes
  • An episode of AD in the previous 6 months that required medical intervention to resolve
  • Significant other neurological, psychiatric, pulmonary, cardiovascular, orthopaedic, or oncological conditions
  • Currently taking part in another clinical trial
  • Upper limb contracture

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

SCINC is an adaptive design Master protocol that seeks to determine if there is "sufficient promise" of beneficial effect of treatment combinations to enhance motor recovery in pre-specified strata of people with a spinal cord injury.

The group in the trial

  • RRULI: Appendix 1Treatment being tested

    In this first arm of SCINC, adults with chronic tetraplegia will be assigned to the RRULI: Appendix 1 intervention.

    Treatment: Therapeutic Intermittent Hypoxia (TIH) + Exercise Training (ET)

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Spinal Cord Injury Neurorecovery Collaboration (SCINC) Master Protocol
Record updated
8 August 2025