Dye imaging to check bowel joins in gynecologic cancer surgery
Tests a green dye and camera to check bowel joins during gynecologic cancer surgery.
Key facts
- Who runs it
- Istanbul University
- Where
- Istanbul, TürkiyeSee the site
- Trial code
- Registry title
- Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery
- Status
- Not yet recruiting
- Phase
- Phase 4
- People taking part
- 50 people, planned
- Started
- 1 Sept 2025
- Expected to end
- 30 Dec 2027
- Type of study
- Interventional
- Treatments tested
- Indocyanine Green
- Near-Infrared Fluorescence Imaging System
- Record updated
- 14 March 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with gynecologic cancer who need surgery that includes removing part of the bowel and reconnecting it. Surgeons use a dye and a special camera to check blood flow at the join.
- Age
- 18 years or older
- Sex
- Women only
- Disease stage
- Gynecologic cancer (ovarian, endometrial, cervical or vulvar) that needs surgery, with a planned bowel resection and anastomosis (reconnection of the bowel).
Main reasons for not taking part
- Known allergy or hypersensitivity to indocyanine green (ICG)
- Pregnant or breastfeeding at the time of surgery
- Severe liver or kidney dysfunction that limits the use of ICG
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Female patients aged 18 years or older
- Diagnosis of gynecologic cancer (ovarian, endometrial, cervical, vulvar) requiring surgical treatment
- Planned bowel resection and anastomosis during gynecologic oncology surgery
- Ability and willingness to provide informed consent
Who cannot take part
- Pregnancy or breastfeeding at the time of surgery
- Known allergy or hypersensitivity to indocyanine green (ICG)
- Severe liver or kidney dysfunction limiting the use of ICG
Where in Türkiye
- Istanbul University, Istanbul Faculty of Medicine, Department of Gynecologic OncologyIstanbul, TürkiyeContact: Yagmur Minareci, Assist. Prof.Not yet recruiting
About the trial
What the trial wants to find out
The goal of this study is to evaluate if indocyanine green (ICG) fluorescence imaging helps reduce complications in bowel surgery performed during gynecologic cancer operations.
Read full original descriptionShow less
The main question it aims to answer is: Does using ICG fluorescence imaging during bowel anastomosis reduce the rate of complications such as leaks, infections, and abscesses within 30 days after surgery? Participants are women aged 18 and older undergoing surgery for gynecologic cancers (such as ovarian, uterine, cervical, or vulvar cancer). During surgery, investigators will inject ICG intravenously, then use a special near-infrared camera to see how well blood flows at the anastomosis site. The investigators will then decide if the reconnection is good enough or needs adjustment.
Researchers will record any complications within the first 30 days after surgery to understand if this imaging method helps reduce surgical risks.
The group in the trial
- ICG Fluorescence Imaging GroupTreatment being tested
Women undergoing gynecologic oncology surgery with bowel resection and anastomosis. Anastomotic perfusion will be evaluated intraoperatively using indocyanine green (ICG) enhanced near-infrared fluorescence imaging.
Treatment: Indocyanine Green and Near-Infrared Fluorescence Imaging System
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluation of Bowel Anastomoses During Gynecologic Oncology Surgery Using Near-Infrared Fluorescence Imaging With Indocyanine Green
- Plain-language title
- Dye imaging to check bowel joins in gynecologic cancer surgeryGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 14 March 2025