MRI Scans to Guide Fertility-Sparing Care for Early Cervical Cancer
Studies MRI scans in women with early cervical cancer who want to keep fertility.
Plain-language title generated from the registry record
Registry title: Role of MRI Assessment in Fertility Sparing Treatment for Cervical Cancer at Staging and Follow-up and for Identification of Risk Factors for Aggressive Disease.
Key facts
- Where
- Rome, ItalySee the site
Where in Italy
- Advanced Radiology Center- Fondazione Policlinico Universitario A. Gemelli IRCCSRome, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Trial code
- NCT06877065
- Record updated
- 14 March 2025
- Original description
The purpose of this study is to investigate the role of MRI, including DWI, in the staging and evaluation of response to fertility sparing treatment, including both primary surgery Protocol FeST-CC V.1.0 of November 10, 2023 Pag. 5 | 23 (RT or CKC) or after NACT, followed by CKC, in patients with ECC (FIGO 2018 stage IB1- IIA1), desiring to preserve their fertility.Read full original descriptionShow less
Role of MRI Assessment in Fertility Sparing Treatment for Cervical Cancer at Staging and Follow-up and for Identification of Risk Factors for Aggressive Disease.
The purpose of this study is to investigate the role of MRI, including DWI, in the staging and evaluation of response to fertility sparing treatment, including both primary surgery Protocol FeST-CC V.1.0 of November 10, 2023 Pag. 5 | 23 (RT or CKC) or after NACT, followed by CKC, in patients with ECC (FIGO 2018 stage IB1- IIA1), desiring to preserve their fertility.
Inclusion: Patients with cervical cancer FIGO stage up to IB2-IIA1 (T size < 4 cm) wishing to preserve fertility treated at the Oncological Gynecology Unit of Foundation Policlinico Universitario Agostino Gemelli; absence of nodal disease,; no menopausal status; wish to preserve fertility; refusal of radical treatment; Patients who had a pre-treatment and post-treatment magnetic resonance imaging; Availability of digital MR images and histopathological samples.
Exclusion: Patients aged under 18 years; Neuroendocrine cervical tumours or other rare histology, such as glassy cells or clear cell carcinoma non-HPV related adenocarcinoma; ongoing pregnancy at the time of diagnosis; Patients without available MR images on digital media or with low quality images.