Studies autism-like traits and sensory profiles in children with Prader-Willi syndrome
Compares autism-like traits and sensory features in children with Prader-Willi syndrome.
Plain-language title generated from the registry record
Registry title: Autistic Symptomatology and Sensory Profile in Children With Prader-Willi Syndrome
Key facts
- Where
- Toulouse, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 3 and 16 years old?
Source: NCT06877715, who can take part
Where in France
- Children HospitalToulouse, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Toulouse
- Trial code
- NCT06877715
- Record updated
- 8 May 2025
- Original description
Prader-Willi Syndrome (PWS) is a rare neurodevelopmental disorder stemming from genetic damage in the 15q11-q13 region, leading to hypothalamic dysfunction. Individuals with PWS often exhibit social interaction challenges, intellectual deficits, significant eating disorders, mood disturbances, and sensory-related autistic features. Although PWS is recognized by DSM-5 as a genetic cause of Autism Spectrum Disorder (ASD), ASD diagnosis in PWS remains rare in France. The CASSPER study aims to investigate the distinct autistic and sensory profiles in children with PWS, also analyzing the potential impact of early oxytocin treatment on these manifestations, in line with recommendations for early and tailored intervention.Read full original descriptionShow less
Autistic Symptomatology and Sensory Profile in Children With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is a rare neurodevelopmental disorder stemming from genetic damage in the 15q11-q13 region, leading to hypothalamic dysfunction. Individuals with PWS often exhibit social interaction challenges, intellectual deficits, significant eating disorders, mood disturbances, and sensory-related autistic features. Although PWS is recognized by DSM-5 as a genetic cause of Autism Spectrum Disorder (ASD), ASD diagnosis in PWS remains rare in France. The CASSPER study aims to investigate the distinct autistic and sensory profiles in children with PWS, also analyzing the potential impact of early oxytocin treatment on these manifestations, in line with recommendations for early and tailored intervention.
Inclusion: Child with genetically confirmed PWS and identification of genetic subtype; Child aged between 3 and 16 years; Hospitalisation or multidisciplinary consultation planned for the child's routine follow-up at one of the investigating centres; No parental/legal guardian objection.
Exclusion: Change in psychotropic treatment (start, change in dose or discontinuation) in the past 3 months; Inability to provide clear information to parents/legal guardian; Not covered by social security.