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Studying how people with epilepsy form memories in everyday life

Records brain activity and daily-life sensor data in people with epilepsy and implanted devices.

Plain-language title generated from the registry record
Registry title: Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings

Key facts

Where
Salt Lake City, United StatesSee the site

Where in United States

  • Clinical Neurosciences Center, University of UtahSalt Lake City, United StatesTaking people

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Trial details

Who runs it
University of Utah
Trial code
NCT06883981
Record updated
8 April 2025
Original description
The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted neurostimulation devices (e.g., NeuroPace RNS) for epilepsy treatment. The main questions it aims to answer are:Read full original descriptionShow less

Capturing Autobiographical Memory Formation in People Moving Through Real-World Spaces Using Synchronized Wearables and Intracranial Recordings of EEG

The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted neurostimulation devices (e.g., NeuroPace RNS) for epilepsy treatment. The main questions it aims to answer are:

How does the brain encode and retrieve real-world autobiographical memories? Can multimodal data integration enhance our understanding of memory-related cognitive and neural mechanisms?

Participants will:

* Use a smartphone-based recording application (CAPTURE app) to collect real-world data. * Have their wearable sensor data (e.g., audio-visual, accelerometry, GPS, autonomic physiology, eye tracking) synchronized with invasive neural recordings.

Researchers will analyze these multimodal data streams to develop new analytic approaches for studying memory formation in naturalistic settings, with the long-term goal of informing neuromodulation-based memory enhancement treatments for individuals with memory disorders.

Inclusion: 18 years of age or older; healthy to minor cognitive impairment.

Exclusion: more than minor cognitive impairment; younger than 18 years of age.

ClinicalTrials.gov NCT06883981