Wound Care Method Tested After Soft Tissue Sarcoma Surgery in Adults
Compares two wound closure methods after sarcoma removal from groin and thigh.
Plain-language title generated from the registry record
Registry title: SAVE Studie- SArcoma Surgery With Vacuum Enhanced Wound Treatment Randomised Study to Evaluate the Wound Management in Sarcoma Surgery
Key facts
- Where
- Hamburg, GermanySee the site
Where in Germany
- Universitätsklinikum Hamburg-EppendorfHamburg, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitätsklinikum Hamburg-Eppendorf
- Trial code
- NCT06889532
- Record updated
- 21 March 2025
- Original description
The aim of this study is to evaluate local complications following sarcoma resection in the groin and thigh regions with regard to the planned wound closure method. To this end, temporary soft tissue coverage using a vacuum-assisted closure (VAC) system and delayed secondary closure with wound sutures and drainage placement will be compared to primary closure with drainage in terms of wound infections, revisions, and seroma formation.Read full original descriptionShow less
SAVE Studie- SArcoma Surgery With Vacuum Enhanced Wound Treatment Randomised Controlled Study to Evaluate the Wound Management in Sarcoma Surgery
The aim of this study is to evaluate local complications following sarcoma resection in the groin and thigh regions with regard to the planned wound closure method. To this end, temporary soft tissue coverage using a vacuum-assisted closure (VAC) system and delayed secondary closure with wound sutures and drainage placement will be compared to primary closure with drainage in terms of wound infections, revisions, and seroma formation.
Inclusion: Patients must be over 18 years old; Patients of any gender and background can be included; The largest tumor diameter on imaging must be at least 5 cm. Preoperative imaging is required to assess tumor dimensions; Sarcomas must be located in the lower extremity or groin; Cases must be discussed preoperatively at an interdisciplinary tumor board; Patients must provide informed consent to participate in the study.
Exclusion: Patients with local recurrences or prior wound healing complications in the surgical area; for whom direct closure is not possible during the initial surgery due to the extent of resection; Patients with ulcerating or infected tumors, or those requiring emergency surgery; Tumors smaller than 5 cm and superficial masses; Other Soft Tissue Tumors such as Kaposi sarcoma.