Developing a Blood Test for Early Detection of Colorectal Cancer
Studies a blood test to find colorectal cancer early in adults.
Plain-language title generated from the registry record
Registry title: Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer
Key facts
- Where
- Barcelona, Bilbao, Donostia / San Sebastian, Madrid, Oviedo, Salamanca, Santander, and Zaragoza, SpainSee the 9 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who will have a colonoscopy or surgery to remove a tumor, to build a blood test for early colorectal cancer.
- Age
- Over 18 years
- Sex
- All sexes
- Disease stage
- Colorectal cancer or advanced adenomas; people who will have a colonoscopy or surgery to remove a tumor (CRC).
- Earlier treatment
- People who had chemotherapy or radiotherapy before cannot join.
Main reasons for not taking part
- Any cancer in the 5 years before joining
- Previous chemotherapy or radiotherapy
- Non-advanced adenomas, serrated polyps, Familial Adenomatous Polyposis or Lynch Syndrome
- Colonoscopy or polypectomy in the previous 5 years
- Inadequate bowel preparation for colonoscopy, or hemolyzed plasma
Read by machine on 12 November 2026.
Where in Spain
- Hospital Sant RafaelBarcelona, SpainContact: Marta JimenezNo longer taking part
- Hospital Universitario Vall d'HebronBarcelona, SpainContact: Marta JimenezNo longer taking part
- Hospital Universitario de CrucesBilbao, SpainContact: Marta JimenezTaking people
- Policlinica Gipuzkoa HospitalDonostia / San Sebastian, SpainContact: Marta JimenezNo longer taking part
- MD Anderson Cancer CentreMadrid, SpainContact: Marta JimenezNo longer taking part
- Hospital Centro Médico de AsturiasOviedo, SpainContact: Marta JimenezTaking people
- Hospital Universitario De SalamancaSalamanca, SpainContact: Marta JimenezTaking people
- Hospital Universitario Marqués de ValdecillaSantander, SpainContact: Marta JimenezNo longer taking part
- Hospital Clinico Universitario Lozano BlesaZaragoza, SpainContact: Marta JimenezTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- ADVANCED MARKER DISCOVERY S.L.
- Trial code
- NCT06889883
- Record updated
- 1 October 2025
- Original description
This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical data of patients diagnosed with CRC or AA and healthy individuals.Read full original descriptionShow less
Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer Based on Molecular Markers and Risk Factors Identified With Artificial Intelligence Tools
This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical data of patients diagnosed with CRC or AA and healthy individuals.
Inclusion: Patients over the age of 18 who are able to understand the participant information and sign the informed consent; Patients who are going to undergo colonoscopy or surgical resection for tumor (CRC).
Exclusion: Patients who had developed any type of cancer in the 5 years prior to their participation in this study; Patients who have received previous chemotherapy or radiotherapy; Patients who have undergone colonoscopy/polipectomy in the previous 5 years; Patients diagnosed with non-advanced adenomas, serrated polyps, Familial Adenomatous Polyposis or Lynch Syndrome; Patients with inadequate bowel preparation for colonoscopy; Patients with hemolyzed plasma.