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Studies how alexithymia relates to chronic migraine frequency

Looks at whether difficulty recognizing emotions links to migraine frequency in people.

Plain-language title generated from the registry record
Registry title: Studio TIARA: Alessitimia ed Emicrania Cronica

Key facts

Where
Alessandria, ItalySee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 12 and 65 years old?

Source: NCT06891053, who can take part

Where in Italy

  • Azienda Sanitaria Locale di Alessandria (ASL AL)Alessandria, ItalyNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Azienda Sanitaria Locale di Alessandria
Trial code
NCT06891053
Record updated
28 October 2026
Original description
The aim of this observational, cross-sectional study is to investigate the relationship between alexithymia and migraine frequency (considering alexithymia a condition that can influence the severity of the clinical phenotype of migraine, favoring its chronicization), in an analysis adjusted for psychiatric comorbidity (for anxiety and depression, potentially influencing migraine chronicization) and for personalogical factor represented by apathy.Read full original descriptionShow less

Studio TIARA: Alessitimia ed Emicrania Cronica

The aim of this observational, cross-sectional study is to investigate the relationship between alexithymia and migraine frequency (considering alexithymia a condition that can influence the severity of the clinical phenotype of migraine, favoring its chronicization), in an analysis adjusted for psychiatric comorbidity (for anxiety and depression, potentially influencing migraine chronicization) and for personalogical factor represented by apathy.

Inclusion: Diagnosis of episodic migraine with or without aura, chronic migraine and/or MOH according to ICHD-3 2018 criteria; Patients aged 12-65 years; Female patients.

Exclusion: Comorbidities for major internal diseases (hepatopathy, nephropathy, heart failure, etc.); Alcohol or substance abuse disorder (eoin, cocaine, cannabis, hallucinogens); Ongoing major depressive episode; Language barrier; Low cultural/cognitive level; No informed consent.

ClinicalTrials.gov NCT06891053