Studies how alexithymia relates to chronic migraine frequency
Looks at whether difficulty recognizing emotions links to migraine frequency in people.
Key facts
- Who runs it
- Azienda Sanitaria Locale di Alessandria
- Where
- Alessandria, ItalySee the site
- Trial code
- Registry title
- Studio TIARA: Alessitimia ed Emicrania Cronica
- Status
- Enrolling by invitation
- People taking part
- 350 people, planned
- Started
- 30 May 2022
- Expected to end
- 31 Dec 2027
- Type of study
- Observational
- Record updated
- 28 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for girls and women aged 12 to 65 with episodic migraine, chronic migraine or medication-overuse headache. It studies how alexithymia relates to how often migraine happens.
- Age
- 12 to 65 years
- Sex
- Female only
- Disease stage
- Episodic migraine with or without aura, chronic migraine and/or medication-overuse headache (MOH), diagnosed by ICHD-3 2018 criteria
Main reasons for not taking part
- Ongoing major depressive episode
- Major internal diseases such as liver disease, kidney disease or heart failure
- Alcohol or substance abuse disorder (heroin, cocaine, cannabis, hallucinogens)
- Language barrier
- Low cultural or cognitive level
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Diagnosis of episodic migraine with or without aura, chronic migraine and/or MOH according to ICHD-3 2018 criteria
- Patients aged 12-65 years
- Female patients
Who cannot take part
- Comorbidities for major internal diseases (hepatopathy, nephropathy, heart failure, etc.)
- Alcohol or substance abuse disorder (eoin, cocaine, cannabis, hallucinogens)
- Ongoing major depressive episode
- Language barrier
- Low cultural/cognitive level
- No informed consent
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 65 years old?
Where in Italy
- Azienda Sanitaria Locale di Alessandria (ASL AL)Alessandria, ItalyNo longer taking part
About the trial
What the trial wants to find out
The aim of this observational, cross-sectional study is to investigate the relationship between alexithymia and migraine frequency (considering alexithymia a condition that can influence the severity of the clinical phenotype of migraine, favoring its chronicization), in an analysis adjusted for psychiatric comorbidity (for anxiety and depression, potentially influencing migraine chronicization) and for personalogical factor represented by apathy.
The group in the trial
- Diagnosis of episodic migraine without or with aura, chronic migraine, and/or MOH
Female patients, aged 12-65 years, diagnosed with episodic migraine without or with aura, chronic migraine, and/or MOH according to the criteria of ICHD-3 2018
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Studio TIARA: Alessitimia ed Emicrania Cronica
- Plain-language title
- Studies how alexithymia relates to chronic migraine frequencyGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06891053, who can take part
- Record updated
- 28 October 2026