Study of an Oral Fluid Testing Approach
Key facts
- Who runs it
- Boston Children's Hospital
- Where
- Boston, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 27 Oct 2025
- Expected to end
- Jun 2027
- Type of study
- Observational
- Treatments tested
- Biologic testing for THC
- Record updated
- 6 November 2026
Who can take part
- Age
- 18 years to 35 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Age 18 to 35 years
- Cannabis use on >=1x/week in the past 30 days
- Ownership of a portable device that is capable of videoconference and videorecording (i.e., smartphone, tablet computer, or laptop computer)
- Ability to read and speak English
- Availability for duration of the study (3-4 weeks)
- To proceed to oral fluid testing, positive result for urinary TCH-COOH
Who cannot take part
- Inability/unwillingness to provide contact information; Individuals age 18-35 are invited to screen here: https://redcap.link/softa-bch
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 35 years old?
Where in United States
- Boston Children's HospitalBoston, United StatesContact: Lydia A. Shrier, MD, MPHTaking people
About the trial
What the trial wants to find out
The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-35 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits across ~ 3-4 weeks and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (~ Day 7; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (~ Day 28; TLFB interview, urine test, oral fluid test, survey, interview).
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Individuals age 18-35 are invited to screen here: https://redcap.link/softa-bch
The group in the trial
- Prospective community sample
Community sample of 200 younger adults aged 18-35 years who have used cannabis in the past 30 days at baseline, report use frequency of ≥1x/week at baseline, and have a positive test for urinary 11-nor-9-carboxy-delta-9-tetrocannabinol (THC-COOH) at the Day-7 visit
Treatment: Biologic testing for THC
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Oral Fluid Testing to Assess Cannabis Non-Use in Remote Clinical Trials
- Fit questions
- Built from NCT06891235, who can take part
- Record updated
- 6 November 2026