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Taking people in CzechiaNo phase

Exercise Program Tested for People With Parkinson's Disease

Tests strength plus endurance training against endurance training alone in adults with Parkinson's disease.

Plain-language title generated from the registry record
Registry title: Strength-Endurance Circuit Training in Parkinson's Disease

Key facts

Where
Prague, CzechiaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Source: NCT06893055, who can take part

Where in Czechia

  • Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in PraguePrague, CzechiaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
General University Hospital, Prague
Trial code
NCT06893055
Record updated
9 April 2025
Original description
The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.Read full original descriptionShow less

Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.

- Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?

Participants will:

* undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement, * visit the clinic twice a week for 1-hour training sessions. * selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Inclusion: age ≥18 years; diagnosis of idiopathic Parkinson´s disease; Hoehn-Yahr Scale ≤ 2,5; stable dopaminergic medication.

Exclusion: age ≥75 years; Hoehn-Yahr Scale ≥ 2,5; deep brain stimulation; presence of freezing; Camptocormia; inability to walk without support; inability to perform study procedures; limiting co-morbidities; attendance at training sessions below 70%.

ClinicalTrials.gov NCT06893055