Studies cortisol changes and low blood sugar after weight-loss surgery
Studies whether cortisol changes contribute to low blood sugar after bariatric surgery.
Plain-language title generated from the registry record
Registry title: Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?
Key facts
- Where
- Esbjerg, DenmarkSee the site
Where in Denmark
- Esbjerg HospitalEsbjerg, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Esbjerg Hospital - University Hospital of Southern Denmark
- Trial code
- NCT06896682
- Record updated
- 13 March 2026
- Original description
The goal of this observational study is to learn about how bariatric surgery affects the metabolism of cortisol.Read full original descriptionShow less
Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?
The goal of this observational study is to learn about how bariatric surgery affects the metabolism of cortisol.
The main question it aims to answer is whether changes in cortisol contribute to the development of reactive hypoglycemia?
100 individuals who have previously undergone bariatric surgery, are planned to be included.
Inclusion: Participants must have undergone one of the following bariatric procedures at least 12 months prior:; Roux-en-Y gastric bypass; Gastric sleeve.
Exclusion: Use of corticosteroid medications, such as prednisolone; Use of opiod-containing medication; Use of medications containing estrogen, such as hormone therapy for menopause; Previously diagnosed reactive hypoglycemia after bariatric surgery requiring medical treatment; Nephrotic syndrome (kidney disease with protein loss in urine), liver cirrhosis, or severe malnutrition, as these conditions reduce cortisol-binding globulin (CBG) levels, affecting total cortisol concentration; Known adrenal disease affecting cortisol metabolism, including autonomous cortisol production and Cushing's syndrome; Diabetes that does not require medical treatment; Pregnancy and breastfeeding.