Taking people in FranceNo phase
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
Key facts
- Who runs it
- Rennes University Hospital
- Where
- Bain-de-Bretagne, Bouaye, Breteil, Cesson-Sévigné, Combourg, Contres, Corps-Nuds, Crac'h, Dol-de-Bretagne, Guer, Iffendic, Joué Les Tours, Jugon-les-Lacs, La Chapelle-des-Fougeretz, La Chapelle-Saint-Ursin, Nantes, Pleudihen-sur-Rance, Ploërmel, Pont-Saint-Martin, Questembert, Rennes, Rouziers-de-Touraine, Saint-Brice-en-Coglès, Saint-Gilles-Croix-de-Vie, Saint-Ouen-des-Alleux, Saint-Romain-sur-Cher, Sancerre, Sully-sur-Loire, Talensac, Tigy, and Vildé-Guingalan, FranceSee the 32 sites
- Trial code
- Status
- Recruiting
- People taking part
- 136 people, planned
- Started
- 14 Oct 2025
- Expected to end
- 14 Oct 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- "Standard care" control group (without hypnosis)
- Experimental group: "E2R hypnosis"
- Record updated
- 19 August 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Patient aged 18 or over,
- Patient suffering from chronic insomnia according to the DSM-5 definition, whether or not treated with psychotropic drugs:; At least one of the following sleep disorders: difficulty in falling asleep, difficulty in maintaining sleep, waking up too early and inability to go back to sleep, and * At least 3 nights a week for at least 3 months, and * In an adequate night-time sleep context, and * With at least one significant impact on, or impairment of, social, occupational or behavioral functioning, and * Insomnia not attributable to the physiological effects of a substance, and * Insomnia not explicable by a medical condition or mental disorder
- Patient willing to undergo hypnotherapy for 4 sessions of 30 min over 6 weeks,
- Patient whose treating physician is the investigator,
- Patient able to give free, informed, written consent,
- Patient affiliated to the French social security system
Who cannot take part
- Patients receiving or having received one or more hypnotherapy sessions (for any reason) in the last 5 years prior to inclusion,
- Patient participating in another study involving the treatment of insomnia or another pathology having an impact on sleep disorders,
- Patient unable to complete a self-administered questionnaire,
- Patients with poor or no understanding of the French language,
- Patients unable to attend hypnotherapy consultations,
- Deaf or hard-of-hearing patients without hearing aids,
- Patient under legal protection (safeguard of justice, curatorship, guardianship) or deprived of liberty,
- Women declaring themselves pregnant or breastfeeding
Where in France
- Cabinet médicalBain-de-Bretagne, FranceContact: Elise RIDARD, MDTaking people
- Cabinet médical de PlaisanceBouaye, FranceContact: Ségolène AIRIEAU, MDTaking people
- Cabinet médical de BreteilBreteil, FranceContact: François TANGUY, MDTaking people
- Cabinet médicalCesson-Sévigné, FranceContact: Adeline PFORR, MDTaking people
- Cabinet médical du LinonCombourg, FranceContact: Frédéric MAS, MDTaking people
- Cabinet médical SycamoreContres, FranceContact: Aurélie VEISLINGERNo longer taking part
- Cabinet médical de Corps NudsCorps-Nuds, FranceContact: Mathilde NGUYEN, MDNot yet recruiting
- Cabinet médical des EmbrunsCrac'h, FranceContact: Isabelle EZANNO, MDTaking people
- Pôle Santé PhysiomastDol-de-Bretagne, FranceContact: Fabienne BENOIT-ROLLAND, MDTaking people
- MSP de l'EsplanadeGuer, FranceContact: Sandra LE FLOCH, MDTaking people
- Maison médicaleIffendic, FranceContact: Emilie JAMOIS, MDTaking people
- Cabinet Médical ChantepieJoué Les Tours, FranceContact: Sophie LIZE, MDTaking people
- Cabinet Médical de Jugon-Les-Lacs -Saint-IgneucJugon-les-Lacs, FranceContact: Madeline LASSERRE, MDTaking people
- Maison médicale des LongraisLa Chapelle-des-Fougeretz, FranceContact: Marie LELIEVRE, MDTaking people
- Cabinet médicalLa Chapelle-Saint-Ursin, FranceContact: Marie-Louise DUGUE, MDTaking people
- Cabinet médical du Lion d'OrNantes, FranceContact: Elsa HAUTREUX, MDTaking people
- Maison médicale LaennecPleudihen-sur-Rance, FranceContact: Nicolas GUILLERM, MDTaking people
- Maison De Santé De RonsouzePloërmel, FranceContact: Emilie RUSQUET, MDTaking people
- Cabinet médical Les Petits PontsPont-Saint-Martin, FranceContact: Elodie DUBUISSON, MDTaking people
- Maison de Santé de QuestembertQuestembert, FranceContact: Marielle VINATIER, MDTaking people
- Cabinet médicalRennes, FranceContact: Anne-Sophie LEJEAU, MDTaking people
- Cabinet médical OlecRennes, FranceContact: Pierre LE DOUARON, MDTaking people
- Maison médicale pluridisciplinaireRouziers-de-Touraine, FranceContact: Flora LEAUTETaking people
- Maison médical de Maen rochSaint-Brice-en-Coglès, FranceContact: Anne-Claire DUFLOT, MDTaking people
- Maison médicaleSaint-Gilles-Croix-de-Vie, FranceContact: Etienne JULIEN, MDTaking people
- Maison de soin du CouesnonSaint-Ouen-des-Alleux, FranceContact: Pierre GUE, MDTaking people
- Cabinet médicalSaint-Romain-sur-Cher, FranceContact: Mathilde GERY, MDTaking people
- Maison de santéSancerre, FranceContact: Florence LAUVERJAT, MDTaking people
- Cabinet médical de la BlanchisserieSully-sur-Loire, FranceContact: Philippe MALLET, MDTaking people
- Maison de santéTalensac, FranceContact: Lucie MURGALE, MDTaking people
- Cabinet des médecins généralistes de TIGYTigy, FranceContact: Patrick DEFREMONT, MDTaking people
- Cabinet médicalVildé-Guingalan, FranceContact: Ronan QUERIC, MDTaking people
About the trial
What the trial wants to find out
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity. Cognitive-behavioral therapy (CBT) is recommended by the HAS as a non-pharmaceutical first-line therapy for chronic insomnia. Despite evidence of their efficacy in chronic insomnia, these therapies remain underdeveloped in France (few practitioners, time-consuming for the patient). Hypnotherapy is another non-drug intervention suitable for routine outpatient care. Among the hypnosis methods practiced in France, E2R (Emotion, Regression, Repair) is a hypnotherapy method used in general practice, particularly for chronic insomnia. To date, no clinical trials have been carried out to demonstrate its effectiveness in this pathology.
Read full original descriptionShow less
The HypERR study is a multicenter, randomized, open-label study designed to evaluate the efficacy of a hypotherapy method called E2R in the management of chronic insomnia, by comparing it with standard care (without hypnosis).
The 2 groups in the trial
- Standard careExisting treatment, for comparison
Patients will receive the usual care offered by their GP, the investigator in the study (except hypnosis).
Treatment: "Standard care" control group (without hypnosis)
- E2R hypnosisTreatment being tested
4 x 30-minute hypnotherapy sessions over 6 weeks by the hypnotherapist using the E2R method (with self-hypnosis)
Treatment: Experimental group: "E2R hypnosis"
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care
- Record updated
- 19 August 2026