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Monitoring brain function after serious brain injury in intensive care

Studies how brain blood flow control and monitoring signals relate in adults with brain injury.

Plain-language title generated from the registry record
Registry title: Multimodal Monitoring Study in Neuro Critical Care

Key facts

Where
France, FranceSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 90 years old?

Source: NCT06900101, who can take part

Where in France

  • Hopital Pierre WertheimerFrance, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Hospices Civils de Lyon
Trial code
NCT06900101
Record updated
28 March 2025
Original description
During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders.Read full original descriptionShow less

Multimodal Monitoring Study in Neuro Critical Care

During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders.

Hence, neurological monitoring of brain oxygen consumption, metabolic disorders, electrical activity is used to follow and prevent delayed cerebral injuries. Among those instruments, numerous are often described: intra cranial pressure monitoring, brain tissue oxygen pressure monitoring, scalp electroencephalography, continuous electroencephalography and Near infrared Red Spectroscopy (NIRS).

Even if the value of some of those technologies are well known, many remain part of a research domain. Here we will not only try to study the correlation between different cerebral autoregulation's index described in the scientific literature but also will we try to identify and describe EEG and cardiorespiratory changes during the first week following brain injury. The objective of this study is to investigate the pathophysiology of acute brain injury and explore potent biomarkers of multimodal monitoring during the first week following acute brain injury.

Inclusion: - Patients hospitalized in neurologic critical care in Wertheimer Hospital, Bron; Monitored with the CNS MOBERG® monitoring system.

Exclusion: - Refusal to participate; Patients under legal protection.

ClinicalTrials.gov NCT06900101