Comparing Sweat Collection Sites for Cystic Fibrosis Testing in Infants
Compares sweat collection from the thigh and forearm in infants under 6 months.
Plain-language title generated from the registry record
Registry title: Sweat Testing in Infants: Comparing Sweat Collection on Upper Vs Lower Limbs
Key facts
- Where
- Jette, BelgiumSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for babies under 6 months old who need a sweat test for cystic fibrosis. It compares sweat collected from the forearm with sweat collected from the thigh.
- Age
- From 10 Days to 6 Months
- Sex
- All sexes can join.
Main reasons for not taking part
- Chromosome abnormalities
- Metabolic abnormalities
- Heart disease (cardiopathies)
- Eczema
- Important skin lesions on the limbs
Read by machine on 12 November 2026.
Where in Belgium
- UZ BrusselJette, BelgiumContact: Elke De Wachter, Prof. Dr.No longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Universitair Ziekenhuis Brussel
- Trial code
- NCT06902363
- Record updated
- 30 March 2025
- Original description
The goal of this study is to compare the rate of Quantity Not Sufficient (QNS) during sweat collection in infants under 6 months of age, using the Macroduct Advanced device for sweat testing. The main question it aims to answer is:Read full original descriptionShow less
Sweat Testing in Infants: a Comparative Study Investigating the Collection of Sweat on the Upper Limbs Compared to the Lower Limbs
The goal of this study is to compare the rate of Quantity Not Sufficient (QNS) during sweat collection in infants under 6 months of age, using the Macroduct Advanced device for sweat testing. The main question it aims to answer is:
Does sweat collection from the thigh (lower limb) reduce the QNS rate compared to the forearm (upper limb) in infants? Do chloride concentration levels differ between sweat collected from the forearm and thigh in the same infants?
Inclusion: minimal 3,000 kg; after a positive newborn screening (NBS) test. During this test, newborns are screened for rare diseases including CF. In case of a positive NBS test for CF, a sweat test is routinely performed to confirm or withdraw the diagnosis; after clinical assessment for CF, with ST as diagnostic step; siblings of patients with CF in order to exclude CF; CF patients who are willing to participate; Healthy infants, born at the maternity unit of UZ Brussel, of which parents are willing to participate.
Exclusion: use of systemic corticosteroids; chromosome abnormalities; metabolic abnormalities; cardiopathies; eczema; important skin lesions on the limbs; critically ill patients (for example hemodynamically unstable).