Studies how vision rehabilitation affects anxiety and depression in people with macular degeneration
Studies whether vision rehabilitation changes anxiety and depression in older adults with advanced macular degeneration.
Plain-language title generated from the registry record
Registry title: Visual Rehabilitation and Depression in Visually Impaired Patients With AMD
Key facts
- Where
- Rome, ItalySee the site
Where in Italy
- Irccs Fondazione G. B. BiettiRome, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione G.B. Bietti, IRCCS
- Trial code
- NCT06906003
- Record updated
- 1 June 2026
- Original description
Purpose: The aim of this study is to evaluate the impact of visual rehabilitation in visually impaired patients with advanced AMD by the use of questionnaires on the anxiety and depression status.Read full original descriptionShow less
Evaluation of the Impact of Visual Rehabilitation on Anxiety and Depression Severity of Visually Impaired Patients With Advanced Age Related Macular Degeneration
Purpose: The aim of this study is to evaluate the impact of visual rehabilitation in visually impaired patients with advanced AMD by the use of questionnaires on the anxiety and depression status.
Study design: prospective observational study. The study is carried out at the IRCCS Fondazione G.B.Bietti and at the UO Visual Rehabilitation, S. Alessio - Margherita di Savoia.
Study procedures: Visit 1 (screening visit, at IRCCS Fondazione Bietti) After signing the informed consent, all patients received a complete ophthalmological examination, non-invasive diagnostic tests as optical coherence tomography, autofluorescence and microperimetry, and have to complete the questionnaires on the state of anxiety and depression (GAD-7 and PHQ-9).
Visit 2 (at the Sant'Alessio Institute) for a 60-day visual rehabilitation program scheduled in 5 group meetings.
Visit 3 (end-of-study visit, at IRCCS Fondazione G.B. Bietti) complete ophthalmological examination, as per clinical practice, non-invasive diagnostic tests such as microperimetry, optical coherence tomography and autofluorescence and administration of the Patient Health Questionnaire-9 (PHQ-9) questionnaires for depression and the General Anxiety Disorder (GAD-7) questionnaires for anxiety.
Inclusion: Subjects ≥ 55 years; Moderate and severe visual impairment (BCVA ≥1/10 and ≤2/10); Diagnosis of advanced non-exudative age-related macular degeneration (AMD); Informed consent freely granted and acquired before the start of the study; Ability to understand and willingness to follow the study instructions and procedures.
Exclusion: Visual impairment due to other ocular diseases; Mild visual impairment or partial or total blindness; Exudative age-related macular degeneration undergoing intravitreal drug treatment.