NCT06907693Completed
The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI
The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI, a Non-Invasive, Functional Respiratory Imaging System
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
Explore the impact of drug candidate CS1 on pathological vascular remodeling of small pulmonary arteries in the disease pulmonary arterial hypertension (PAH). This sub-study for CS1-004 aims to utilize FRI, an innovative, non-invasive imaging technology to visualize how long-term use of CS1 influences structural changes in pulmonary arteries. This sub-study seeks to provide valuable insights into the potential of CS1 to transform PAH treatment in some patients enrolled in the Expanded Access Program (CS1-004).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 7 (actual)
- First submitted
- 27 Mar 2025
- Start date
- Mar 2025
- Primary completion date
- Dec 2025
- Lead sponsor
- Prisma Health-Upstate
- NCT number
- NCT06907693
What you commit to
- Study type: Observational
- Participants enrolled: 7
- From Mar 2025 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy to Iodine contrast agents
Lab values
- eGFR \<30 mL/min/1.73m2 as calculated by Modification of Diet in Renal Disease (MDRD)
Other
- Inability to undergo a CT pulmonary angiography scan (i.e., claustrophobia)
- Individuals who are pregnant or who become pregnant during the sub-study
Who the study is looking for
- Participation in the CS1-004 clinical trial
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Prisma Health Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.