Comparing anesthesia types and body inflammation in people having weight-loss surgery
Compares anesthesia with and without opioids for inflammation after weight-loss surgery.
Plain-language title generated from the registry record
Registry title: Modulation of the Inflammatory Response in Bariatric Surgery
Key facts
- Where
- Barcelona, SpainSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06915558, who can take part
Where in Spain
- Hospital HM Nou DelfosBarcelona, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital HM Nou Delfos
- Trial code
- NCT06915558
- Record updated
- 8 April 2025
- Original description
This study will evaluate how different anesthesia techniques affect inflammation after bariatric surgery. Patients will be randomly assigned to receive one of three approaches: opioid-free anesthesia, intravenous anesthesia with opioids, or inhalational anesthesia with opioids.Read full original descriptionShow less
Modulation of the Inflammatory Response to Surgical Trauma: Comparison of Three Anesthetic Techniques in Bariatric Surgery Patients
This study will evaluate how different anesthesia techniques affect inflammation after bariatric surgery. Patients will be randomly assigned to receive one of three approaches: opioid-free anesthesia, intravenous anesthesia with opioids, or inhalational anesthesia with opioids.
The study will measure blood levels of inflammation-related substances (such as IL-6, CRP, cortisol, ESR , WBC and lactate) at several time points before and after surgery. Heart rate variability will also be monitored as an indicator of the body's stress response.
The results may help identify anesthesia strategies that reduce inflammation and improve recovery in patients undergoing bariatric surgery.
Inclusion: Patients scheduled for bariatric surgery; Age 18-65 years; BMI ≥ 30 kg/m²; ASA physical status II-III.
Exclusion: Chronic opioid use before surgery; Severe renal or hepatic failure; Uncontrolled psychiatric disorders; Pregnancy or breastfeeding; Significant intraoperative complications requiring protocol deviation.